Protein Alignment pkaap and rgs-5

DIOPT Version :9

• Sequence 1: NP_609783.1
• Gene: pkaap / 34957
• FlyBaseID: FBgn0040079
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_498229.3
• Gene: rgs-5 / 175794
• WormBaseID: WBGene00004348
• Length: 492
• Species: Caenorhabditis elegans
• Alignment Length: 648
• Identity: 147/648 - (22%)
• Similarity: 254/648 - (39%)
• Gaps: 197/648 - (30%)

  Fly     2 LNYIKRHASRRRSSQDATDAICGQMPAYDVDTNDVAGAGDAANAHKRHSLRSTTSFCDEVFLE-- 64
            |..::|...:.::...||.:               .||....||| |.||.:     |.:.:.
 Worm     5 LGRLRRKKDKEQNGHTATSS---------------DGAYQNGNAH-RDSLVN-----DHICIPAQ 48

  Fly    65 ------AEEEGGVGTTGGGGGGGGGGGGGGAPSDGISLASNDDIFTYNSRLSMNLASIVNDPNCL 123
                  |::...:|:              |:..:||       |.....:|:.:|..::.|.:.|
 Worm    49 RNSLTVAQQSADIGS--------------GSDHEGI-------IVKQKPQLAFSLDRLLIDSSAL 92

  Fly   124 SYFVQYLDTRQALPLIKFYLDIENFKRAALTQEKEEPEEPPRKAIEQSSPHKDDKDVPELKTLCD 188
            |||:||||:...|.||||::.:|.|| ::.:::.:..:|
 Worm    93 SYFIQYLDSTDKLNLIKFWMHVEGFK-SSFSEQIQAAQE-------------------------- 130

  Fly   189 LSMRKPLTDDEKSRIYAETNKQLNRQKSGTDSVLNAELSRASISDAIAIYQKYLIVNASLQVELP 253
            ||:|                                        ||.:||.||:...::..:.||
 Worm   131 LSLR----------------------------------------DAKSIYDKYIDDGSTSSLALP 155

  Fly   254 IVILAHISLLLCGRDKSECSKPIPASCFDEAREFVLEQLERDHVQGFLQSGYYSTYCLELIEGGS 318
            ..|...:.      ||...| |:..||||||::||....|..:...|..|.||..:.||::..|
 Worm   156 RKIKQIVD------DKLSAS-PLQKSCFDEAQDFVKSLFEYRYFDEFQNSVYYKKHELEVLSDG- 212

  Fly   319 VNIYDVLNSELALFYFTEYLEQRQERECLEFWITAINFRKSFACGEEKEEDRKAAQSDAMIIYDK 383
            .::.|:|..:..|..|.|:::::::.:.::|.:...:|..:....|:.|     |..|||.:|:|
 Worm   213 CSLADILKVQPLLLSFLEFIKEKEDHDTIQFLLGCDSFEANLDLMEDSE-----ALGDAMALYEK 272

  Fly   384 YFSLQSECRLWMSQKLRLRVEQAIC----APNEQWQAFDLALLVTAKYLEQKYFADFLKSHIFDN 444
            |||:|:...:.:...:|..:|..||    .||.  :||..|.......|..||.:||||:..:.|
 Worm   273 YFSMQATNMIDLGSAIRAEMESLICEESGRPNR--KAFRTAKTACFFRLHDKYLSDFLKTSYYHN 335

  Fly   445 YVNELKVKRDNSTTHPNLQHTLSLRRAGKSSNGQQQRHRKTLSMSDCTHISQHNTLLASMDQAPS 509
            |:.||:...|.:...|                      ||.           .|...:|.|.|.|
 Worm   336 YLGELQSFIDFTVELP----------------------RKV-----------RNRAASSSDVASS 367

  Fly   510 KTALNHQ-SGNLNIDARQLTNPQLLWQRPVG--------------ALKFGFVNSLGRYERDFEAV 559
            ..:|.|. |.:|.:..:::.:.....|.|.|              :.:...|:.:|||...::
 Worm   368 TDSLTHAFSRHLEVLEKKMNDKDESTQTPTGSPSSSKRSTPRTPRSSRLAEVDEMGRYHALYD-- 430

  Fly   560 DAVALKSQPWSLSVSGSKLKNAMRKLVNLPEDNV--QEEIAWQVAEMIVRDVTSVTLSGKTPP 620
            |:.:...|      ...::|:.:||.:   :.|.  :||||.:||..|:||:..:..|....|
 Worm   431 DSHSQTPQ------KPMRIKSTLRKYL---DKNTLREEEIAEEVARTIIRDMQEMVASSAESP 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pkaap	NP_609783.1	RGS	109..308	CDD:295367	49/198 (25%)
		RGS_AKAP2_2	324..444	CDD:188676	34/123 (28%)
		AKAP10_AKB	561..605	CDD:214003	11/45 (24%)
rgs-5	NP_498229.3	RGS	81..203	CDD:279009	48/195 (25%)
		RGS	214..336	CDD:214613	35/128 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158862
Domainoid	1	1.000	60	1.000	Domainoid score	I7040
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	110	1.000	Inparanoid score	I3459
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D288202at33208
OrthoFinder	1	1.000	-	-		FOG0006831
OrthoInspector	1	1.000	-	-		oto19266
orthoMCL	1	0.900	-	-		OOG6_107972
Panther	1	1.100	-	-	LDO	PTHR13155
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3006
SonicParanoid	1	1.000	-	-		X4922
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.930