Protein Alignment crp and TFAP4

DIOPT Version :9

• Sequence 1: NP_001285976.1
• Gene: crp / 34956
• FlyBaseID: FBgn0001994
• Length: 631
• Species: Drosophila melanogaster
• Sequence 2: NP_003214.1
• Gene: TFAP4 / 7023
• HGNCID: 11745
• Length: 338
• Species: Homo sapiens
• Alignment Length: 406
• Identity: 107/406 - (26%)
• Similarity: 164/406 - (40%)
• Gaps: 155/406 - (38%)

  Fly    91 DSEKRMRREIANSNERRRMQSINAGFQSLRSLLPRHEGEKLSKAAILQQTFQYIVELENQKTQLL 155
            |.|:|:|||||||||||||||||||||||::|:|..:|||||||||||||.:||..||.:||:||
Human    43 DQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRLL 107

  Fly   156 TQNSELKRQVGEHEAGGSGDGGGTNSGGNYNDSNASGGNSTAVAIKKRKLTDNVINIQAISDSSD 220
            .||::|||.:  .|..||..                         |:|:..|           .|
Human   108 QQNTQLKRFI--QELSGSSP-------------------------KRRRAED-----------KD 134

  Fly   221 EGLGSMSPEPMTLLTAGGAAATKLSNAATLLAAKELHESKKQLEKERSLRRLLEDELQMIKRQLY 285
            ||:|  ||:           ..:...|..|  .:|:.|.::||:||||:|.:||::::.::..:|
Human   135 EGIG--SPD-----------IWEDEKAEDL--RREMIELRQQLDKERSVRMMLEEQVRSLEAHMY 184

  Fly   286 SVATAPPGTAVAAASGGSSGAYIPREVIEHTDNFVRSEDLEELGGTVSYVEIDEMTGQQQVVVCS 350
            .                                       |:|......|::.:...|.:::...
Human   185 P---------------------------------------EKLKVIAQQVQLQQQQEQVRLLHQE 210

  Fly   351 SIEELEADAAAEIITED-QVHEEVILSSNSSTESENEVNVNAIAKAYAEGCTSSAAMLQPILQAA 414
            .:|..:.....:::... ..|...::.........:.:||..:..:......|::
Human   211 KLEREQQQLRTQLLPPPAPTHHPTVIVPAPPPPPSHHINVVTMGPSSVINSVSTS---------- 265

  Fly   415 IKATPKVEVERIHEKIVKVKTEKHDLPSMQTAPHYQHSHRQNLETIVQAIRHLEGDHLFADGSGG 479
                                                   ||||:||||||:|:||.
Human   266 ---------------------------------------RQNLDTIVQAIQHIEGT--------- 282

  Fly   480 QEKFGQQQNLQQHHHQ 495
            |||    |.|::...:
Human   283 QEK----QELEEEQRR 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
crp	NP_001285976.1	HLH	97..148	CDD:278439	40/50 (80%)
TFAP4	NP_003214.1	HLH	49..100	CDD:306515	40/50 (80%)
		Leucine-zipper 1	100..120		10/21 (48%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	118..141		11/60 (18%)
		Leucine-zipper 2	151..179		12/29 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	283..338		5/16 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158193
Domainoid	1	1.000	82	1.000	Domainoid score	I8465
eggNOG	1	0.900	-	-		E1_KOG0561
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	151	1.000	Inparanoid score	I4378
Isobase	1	0.950	-	0	Normalized mean entropy	S6439
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1565841at2759
OrthoFinder	1	1.000	-	-		FOG0006895
OrthoInspector	1	1.000	-	-		oto91107
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR15741
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5799
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.810