Protein Alignment twe and MIH1

DIOPT Version :10

• Sequence 1: NP_476633.1
• Gene: twe / 34954
• FlyBaseID: FBgn0002673
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_013750.1
• Gene: MIH1 / 855052
• SGDID: S000004639
• Length: 554
• Species: Saccharomyces cerevisiae
• Alignment Length: 368
• Identity: 101/368 - (27%)
• Similarity: 150/368 - (40%)
• Gaps: 76/368 - (20%)

  Fly    69 LSQNMNGARLDG-TPKSTQ-----RIPANRTLNNFNSLS----SRTLGSFSSSCSSYESGNSLDD 123
            |..|.....:|| :|...|     .:..|...|:...||    |:||.|.:.:.|.....|:.|:
Yeast    69 LLTNHRSKEIDGPSPNIKQLGHRDELDENENENDDIVLSMHFASQTLQSPTRNSSRRSLTNNRDN 133

  Fly   124 EYMDMFEMESAENHNLELPDDLEVLLSGQLKSESNLEEMS--NKKGSLRRCLSMYPSEQPEEAVQ 186
            :                       ||| ::|...:.:..|  ::..||.|..||..|......||
Yeast   134 D-----------------------LLS-RIKYPGSPQRSSSFSRSRSLSRKPSMNSSSNSSRRVQ 174

  Fly   187 EPDQETNMPMKKMQRK--TLSMNDAEIMRALGDEPELIGDLSKPCTLPCLATGIRHRDLKT---- 245
            ..|.:.....:|..:|  .::.|......| ...|.....:...|...|||        ||
Yeast   175 RQDGKIPRSSRKSSQKFSNITQNTLNFTSA-SSSPLAPNSVGVKCFESCLA--------KTQIPY 230

  Fly   246 -------------ISSDTLARLIQGEFDEQLGSQGGYEIIDCRYPYEFLGGHIRGAKNLYTRGQI 297
                         ||.:||..::|....|..  .....|||||:.||:.||||..:.|:::|.::
Yeast   231 YYDDRNSNDFFPRISPETLKNILQNNMCESF--YNSCRIIDCRFEYEYTGGHIINSVNIHSRDEL 293

  Fly   298 QEAF--PTLTSNQENRR----IYVFHCEFSSERGPKLLRYLRSNDRSQHTHNYPALDYPELYILH 356
            :..|  ..|.|:..|..    :.:.||||||.|||.|..:||:.||..:..:||.|.||::.||.
Yeast   294 EYEFIHKVLHSDTSNNNTLPTLLIIHCEFSSHRGPSLASHLRNCDRIINQDHYPKLFYPDILILD 358

  Fly   357 NGYKEFFGLYSQLCQPSQYVPMLAPAH----NDEFRYFRAKTK 395
            .|||..|..:.:||.|.|||.|.:..:    ..|...||.::|
Yeast   359 GGYKAVFDNFPELCYPRQYVGMNSQENLLNCEQEMDKFRRESK 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twe	NP_476633.1	Cdc25	243..363	CDD:238788	49/142 (35%)
MIH1	NP_013750.1	MIH1	1..442	CDD:227436	101/368 (27%)