Protein Alignment twe and MIH1

DIOPT Version :9

• Sequence 1: NP_001260491.1
• Gene: twe / 34954
• FlyBaseID: FBgn0002673
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_013750.1
• Gene: MIH1 / 855052
• SGDID: S000004639
• Length: 554
• Species: Saccharomyces cerevisiae
• Alignment Length: 366
• Identity: 99/366 - (27%)
• Similarity: 149/366 - (40%)
• Gaps: 72/366 - (19%)

  Fly    69 LSQNMNGARLDG-TPKSTQ-----RIPANRTLNNFNSLS----SRTLGSFSSSCSSYESGNSLDD 123
            |..|.....:|| :|...|     .:..|...|:...||    |:||.|.:.:.|.....|:.|:
Yeast    69 LLTNHRSKEIDGPSPNIKQLGHRDELDENENENDDIVLSMHFASQTLQSPTRNSSRRSLTNNRDN 133

  Fly   124 EYMDMFEMESAENHNLELPDDLEVLLSGQLKSESNLEEMSNKKGSLRRCLSMYPSEQPEEAVQEP 188
            :.:.          .::.|        |..:..|:.    ::..||.|..||..|......||..
Yeast   134 DLLS----------RIKYP--------GSPQRSSSF----SRSRSLSRKPSMNSSSNSSRRVQRQ 176

  Fly   189 DQETNMPMKKMQRK--TLSMNDAEIMRALGDEPELIGDLSKPCTLPCLATGIRHRDLKT------ 245
            |.:.....:|..:|  .::.|......| ...|.....:...|...|||        ||
Yeast   177 DGKIPRSSRKSSQKFSNITQNTLNFTSA-SSSPLAPNSVGVKCFESCLA--------KTQIPYYY 232

  Fly   246 -----------ISSDTLARLIQGEFDEQLGSQGGYEIIDCRYPYEFLGGHIRGAKNLYTRGQIQE 299
                       ||.:||..::|....|..  .....|||||:.||:.||||..:.|:::|.:::.
Yeast   233 DDRNSNDFFPRISPETLKNILQNNMCESF--YNSCRIIDCRFEYEYTGGHIINSVNIHSRDELEY 295

  Fly   300 AF--PTLTSNQENRR----IYVFHCEFSSERGPKLLRYLRSNDRSQHTHNYPALDYPELYILHNG 358
            .|  ..|.|:..|..    :.:.||||||.|||.|..:||:.||..:..:||.|.||::.||..|
Yeast   296 EFIHKVLHSDTSNNNTLPTLLIIHCEFSSHRGPSLASHLRNCDRIINQDHYPKLFYPDILILDGG 360

  Fly   359 YKEFFGLYSQLCQPSQYVPMLAPAH----NDEFRYFRAKTK 395
            ||..|..:.:||.|.|||.|.:..:    ..|...||.::|
Yeast   361 YKAVFDNFPELCYPRQYVGMNSQENLLNCEQEMDKFRRESK 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twe	NP_001260491.1	Cdc25	243..363	CDD:238788	49/142 (35%)
MIH1	NP_013750.1	MIH1	1..442	CDD:227436	99/366 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344710
Domainoid	1	1.000	88	1.000	Domainoid score	I1821
eggNOG	1	0.900	-	-		E1_COG5105
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3806
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000931
OrthoInspector	1	1.000	-	-		otm46815
orthoMCL	1	0.900	-	-		OOG6_101194
Panther	1	1.100	-	-	O	PTHR10828
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R583
SonicParanoid	1	1.000	-	-		X695
TreeFam	1	0.960	-	-
	12	11.680