Protein Alignment twe and cdc25a

DIOPT Version :9

• Sequence 1: NP_001260491.1
• Gene: twe / 34954
• FlyBaseID: FBgn0002673
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_001039063.2
• Gene: cdc25a / 733851
• XenbaseID: XB-GENE-5809292
• Length: 527
• Species: Xenopus tropicalis
• Alignment Length: 348
• Identity: 119/348 - (34%)
• Similarity: 173/348 - (49%)
• Gaps: 72/348 - (20%)

  Fly   109 SSSCSSYESGNSLDDEYMDMFEMESAENHNLELPDDLEVLLSGQL--KSESNLEEMSNKKGSLRR 171
            ||:.|:...|:  ||.::||.:.|..|| :.|.|..:..|.:..|  ||..|
 Frog   215 SSAASTSTEGS--DDGFLDMLDGEDLEN-DTEFPCGVASLWTAPLVMKSTEN------------- 263

  Fly   172 CLSMYPSEQP--------EEAVQEPDQETNMPMKKMQRKTLSM---------NDAEIMRAL---- 215
            ||.:.|:.:|        :...:.||::|  |.|..:|:::|.         .::.:||:.
 Frog   264 CLEVRPASEPNCTTKPALKRVERTPDEDT--PEKSKRRRSVSEIAKEELDHDKNSRLMRSKSLSS 326

  Fly   216 --------GDEPELIGDLSKPCTLPCLATGIRHRDLKTISSDTLARLIQGEFDEQLGSQGGYEII 272
                    .|:..||||.||....|.::.  ||::||.|:.:.:..::.|.||..:..   ..||
 Frog   327 QNIESMLDNDQVSLIGDFSKVFLFPTVSG--RHQELKYITPELMVLILNGRFDPFIER---CVII 386

  Fly   273 DCRYPYEFLGGHIRGAKNLYTRGQIQEAF---PTLTSNQENRRIYVFHCEFSSERGPKLLRYLRS 334
            |||||||:.||||:||.||:...:.:|.|   |.: ||...|.|.:|||||||||||::.::||.
 Frog   387 DCRYPYEYEGGHIQGAINLHMEQEAEEYFLKNPVM-SNGSKRVILIFHCEFSSERGPRMCKFLRE 450

  Fly   335 NDRSQHTHNYPALDYPELYILHNGYKEFFGLYSQLCQPSQYVPMLAPAHNDEFRYFRAKTKSWQC 399
            .||.:  :.||.|.||||||||.||||||......|.|..|.||......::.|.||.|:::|
 Frog   451 KDRDR--NEYPQLYYPELYILHGGYKEFFQKCKTYCTPQTYRPMNHEDFKEDLRKFRMKSRTW-- 511

  Fly   400 GEGGDSGIGGGGSRGLRKSRSRL 422
                      .|.|..|:..|||
 Frog   512 ----------AGERSKRELYSRL 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twe	NP_001260491.1	Cdc25	243..363	CDD:238788	60/122 (49%)
cdc25a	NP_001039063.2	M-inducer_phosp	83..331	CDD:284119	31/133 (23%)
		Cdc25	360..478	CDD:238788	61/123 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	199	1.000	Inparanoid score	I3672
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1423329at2759
OrthoFinder	1	1.000	-	-		FOG0000931
OrthoInspector	1	1.000	-	-		otm48637
Panther	1	1.100	-	-	O	PTHR10828
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R583
SonicParanoid	1	1.000	-	-		X695
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	10.100