Protein Alignment twe and cdc-25.4

DIOPT Version :9

• Sequence 1: NP_001260491.1
• Gene: twe / 34954
• FlyBaseID: FBgn0002673
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_496197.2
• Gene: cdc-25.4 / 191612
• WormBaseID: WBGene00000389
• Length: 278
• Species: Caenorhabditis elegans
• Alignment Length: 140
• Identity: 52/140 - (37%)
• Similarity: 75/140 - (53%)
• Gaps: 23/140 - (16%)

  Fly   271 IIDCRYPYEFLGGHIRGAKNLYTRGQIQEAF-------PTLTSNQENRRIYVFHCEFSSERGPKL 328
            |.|||||:|:.||||:||.|:|:..::.:..       .||     ...|.:|:||:|..|||.:
 Worm    81 IFDCRYPFEYFGGHIKGAVNIYSLDELGKYLYDEYGVKSTL-----GGLIPIFYCEYSQVRGPAM 140

  Fly   329 LRYLRSNDRSQHTHNYPALDYPELYILHNGYKEFFGLYS--QLCQPSQYVPMLAPAHNDEFR--- 388
            .|.||..|..::.|...|||:||:|:|..||..|:...|  .||:|..|:.|    |...||
 Worm   141 ARRLRKIDTHRNNHRAAALDFPEIYLLDKGYVNFWSDVSLRDLCEPRYYISM----HARPFRHAL 201

  Fly   389 --YFRAKTKS 396
              |.:.::||
 Worm   202 QQYTQHRSKS 211

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twe	NP_001260491.1	Cdc25	243..363	CDD:238788	39/98 (40%)
cdc-25.4	NP_496197.2	Cdc25	58..176	CDD:238788	40/99 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5105
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3806
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1423329at2759
OrthoFinder	1	1.000	-	-		FOG0000931
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101194
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R583
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.660