Protein Alignment twe and LOC1279787

DIOPT Version :10

• Sequence 1: NP_476633.1
• Gene: twe / 34954
• FlyBaseID: FBgn0002673
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: XP_061504682.1
• Gene: LOC1279787 / 1279787
• VectorBaseID: AGAMI1_005503
• Length: 828
• Species: Anopheles gambiae
• Alignment Length: 521
• Identity: 181/521 - (34%)
• Similarity: 256/521 - (49%)
• Gaps: 147/521 - (28%)

  Fly    23 ENFDPHDADMEYQAKRRKSAVQETPLQWMLKRHIPASTTVLSPITELSQNMNGARLDGTPKSTQR 87
            ::.||:..|..|.|.....|:       |...|..:|.:|    |...|:.:........::.|
Mosquito   334 DDHDPNSMDSGYGASVLNDAL-------MSSLHNSSSGSV----TAAKQSHHSLFQFNQSQTAQ- 386

  Fly    88 IPANRTLNNFNSLSS------RTLGSFSSSCSSYESGNSLDDEYMDMFEMESAENHNLE------ 140
               |.:|:..||.||      |.|...|.|..|.|   |:||  |::|:||:.|:.::|
Mosquito   387 ---NSSLSRHNSASSPASSRGRLLLHSSLSSGSME---SMDD--MELFDMEAMEDDDMEGKGQPG 443

  Fly   141 ------LPDDLEVLLSGQLKSESNLEEM--SNKKGSLRRCLSMYPSE-----QPEEAVQEP---- 188
                  .|..|..|:.|.:|:.:.....  ..|:..:|||||:..:.     |.::.::.|
Mosquito   444 QQSRTQQPSGLSSLICGTIKTTTRTATTPEHQKRPFVRRCLSLTENNNGTVLQQQQQMKTPERYS 508

  Fly   189 -------DQE------------------------------------------------------- 191
                   |||
Mosquito   509 RRMIAIEDQENCNLTPYSSRTEAAVTRCFKRPEPPGISPVQSKRSKMQMDAVAFAPPAVTALDSP 573

  Fly   192 ------TNMPMKKMQRKTLSMNDAEIMRAL---GDEPELIGDLSKPCTLPCLATGIRHRDLKTIS 247
                  ..:|.|.:.:|::|||||:||.||   ..||:||||.||...|| |..| :|||||:||
Mosquito   574 ARTTVLAAVPKKPVYQKSISMNDAQIMSALSRSSSEPDLIGDFSKSYVLP-LMEG-QHRDLKSIS 636

  Fly   248 SDTLARLIQGEFDEQLGSQGGYEIIDCRYPYEFLGGHIRGAKNLYTRGQIQE-------AFPTLT 305
            .||:|||::|::::::.|   ::|||||||||:.||||||||||||:.||.|       |.|.:|
Mosquito   637 GDTMARLVRGDYNDKIAS---FKIIDCRYPYEYEGGHIRGAKNLYTQEQIVEELIQSKTAPPKVT 698

  Fly   306 SNQE---NRRIYVFHCEFSSERGPKLLRYLRSNDRSQHTHNYPALDYPELYILHNGYKEFFGLYS 367
            ..|:   .|.|.||||||||||||||.|:||::||..:..:||||.|||:|:||.||||||..::
Mosquito   699 DGQDGTMRRHIIVFHCEFSSERGPKLSRFLRNHDRILNADSYPALHYPEMYLLHGGYKEFFKAHA 763

  Fly   368 QLCQPSQYVPMLAPAHNDEFRYFRAKTKSWQCGEG----------GDSGIGGGGSRGLRKSRSRL 422
            :||.|..|.|||.|...:.:|:||||::||. |:|          ..|.:.||.:| |.||||||
Mosquito   764 ELCDPIAYRPMLDPDFGEAYRHFRAKSRSWN-GDGTGTVKASATASSSSLAGGPNR-LTKSRSRL 826

  Fly   423 L 423
            :
Mosquito   827 M 827

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twe	NP_476633.1	Cdc25	243..363	CDD:238788	74/129 (57%)
LOC1279787	XP_061504682.1	None