Protein Alignment EndoGI and Xrcc5

DIOPT Version :10

• Sequence 1: NP_609781.1
• Gene: EndoGI / 34953
• FlyBaseID: FBgn0028515
• Length: 359
• Species: Drosophila melanogaster
• Sequence 2: NP_803154.2
• Gene: Xrcc5 / 363247
• RGDID: 3976
• Length: 732
• Species: Rattus norvegicus
• Alignment Length: 314
• Identity: 59/314 - (18%)
• Similarity: 114/314 - (36%)
• Gaps: 109/314 - (34%)

  Fly    33 VKDYQKLIETRVQ---VDEIVDD-DVTKENFDRTAAAARDVIWRLLFDEAGTSQSNTEKASQLLE 93
            :|:.:|...|..|   :|:::|. .:.|:|.:      .|:| ..||..:.......::..|.|
  Rat   438 LKNNKKCTPTEAQLSAIDDLIDSMSLVKKNEE------EDII-EDLFPTSKIPNPEFQRLYQCL- 494

  Fly    94 EYRGDACFYDPTPYNEWIVKLRDEVLKKELLDFWRDVLVKKQLGPCWSRDSDLFDSDDTPPLEFY 158
                                            ..|.:.::::|.|......::.|    ||.|.
  Rat   495 --------------------------------LHRALHLQERLPPIQQHILNMLD----PPTEM- 522

  Fly   159 AHAGCTAPFAASLKVRAAL--------EEQASLD-------QDGPA-----TPTTPGELSADDAA 203
             .|.|..|.:   ||:...        ::|.:..       ::|||     |....|.:|....|
  Rat   523 -KAKCEIPLS---KVKTLFPLTEVVKKKDQVTAQDVFQDNIEEGPAAKKYKTEKEEGHISISSLA 583

  Fly   204 ALSGEFEATLTK---ENPLEEYRTLMKRFVLTKIIVPDSVHQASVKKIAAAAREIIWKLLFDGTP 265
                  |..:||   .||:|.:|.|:::.:.       |..:||::.::...:.:
  Rat   584 ------EGNVTKVGSVNPVENFRVLVRQKIA-------SFEEASLQLMSHIEQFL---------- 625

  Fly   266 SAEDQN------KAAELLQEYKGDA-GFYGPDDYNSWIFNLRDEVLTKELLDFW 312
               |.|      |:.:.::..:.:| .|.....:||::..||::|..|:|..||
  Rat   626 ---DTNETLYFMKSMDCIKALREEAIQFSEEQRFNSFLEGLREKVEIKQLNHFW 676

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EndoGI	NP_609781.1	Ku_PK_bind	31..138	CDD:462604	16/108 (15%)
		Ku_PK_bind	217..323	CDD:462604	22/103 (21%)
Xrcc5	NP_803154.2	Ku_N	9..244	CDD:427470
		KU80	246..542	CDD:238445	26/152 (17%)
		Ku_PK_bind	594..707	CDD:462604	22/103 (21%)