Protein Alignment PRL-1 and Ptp4a1

DIOPT Version :10

• Sequence 1: NP_609780.1
• Gene: PRL-1 / 34952
• FlyBaseID: FBgn0024734
• Length: 176
• Species: Drosophila melanogaster
• Sequence 2: NP_035330.1
• Gene: Ptp4a1 / 19243
• MGIID: 1277096
• Length: 173
• Species: Mus musculus
• Alignment Length: 168
• Identity: 98/168 - (58%)
• Similarity: 127/168 - (75%)
• Gaps: 2/168 - (1%)

  Fly    11 RPAPALIEYKGMKFLITDRPSDITINHYIMELKKNNVNTVVRVCEPSYNTDELETQGITVKDLAF 75
            ||||..:.||.|:||||..|::.|:|.:|.||||..|.|:|||||.:|:|..:|.:||.|.|..|
Mouse     6 RPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPF 70

  Fly    76 EDGTFPPQQVVDEWFEVLKDKYQQNPEACVAVHCVAGLGRAPVLVALALIELGLKYEAAVEMIRD 140
            :||..|..|:||:|..::|.|:::.|..|:|||||||||||||||||||||.|:|||.||:.||.
Mouse    71 DDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIRQ 135

  Fly   141 KRRGAINAKQLSFLEKYKPKARLKHK--NGHKNSCSVQ 176
            |||||.|:|||.:||||:||.||:.|  |||:|:|.:|
Mouse   136 KRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ 173

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PRL-1	NP_609780.1	PTP-IVa	10..163	CDD:350350	89/151 (59%)
Ptp4a1	NP_035330.1	PTP-IVa1	1..167	CDD:350513	94/160 (59%)
		Interaction with ATF5. /evidence=ECO:0000269|PubMed:11278933	97..132		28/34 (82%)