Protein Alignment PRL-1 and Ptp4a1

DIOPT Version :9

• Sequence 1: NP_001260487.1
• Gene: PRL-1 / 34952
• FlyBaseID: FBgn0024734
• Length: 176
• Species: Drosophila melanogaster
• Sequence 2: NP_035330.1
• Gene: Ptp4a1 / 19243
• MGIID: 1277096
• Length: 173
• Species: Mus musculus
• Alignment Length: 168
• Identity: 98/168 - (58%)
• Similarity: 127/168 - (75%)
• Gaps: 2/168 - (1%)

  Fly    11 RPAPALIEYKGMKFLITDRPSDITINHYIMELKKNNVNTVVRVCEPSYNTDELETQGITVKDLAF 75
            ||||..:.||.|:||||..|::.|:|.:|.||||..|.|:|||||.:|:|..:|.:||.|.|..|
Mouse     6 RPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPF 70

  Fly    76 EDGTFPPQQVVDEWFEVLKDKYQQNPEACVAVHCVAGLGRAPVLVALALIELGLKYEAAVEMIRD 140
            :||..|..|:||:|..::|.|:::.|..|:|||||||||||||||||||||.|:|||.||:.||.
Mouse    71 DDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIRQ 135

  Fly   141 KRRGAINAKQLSFLEKYKPKARLKHK--NGHKNSCSVQ 176
            |||||.|:|||.:||||:||.||:.|  |||:|:|.:|
Mouse   136 KRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ 173

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PRL-1	NP_001260487.1	PTP-IVa	10..163	CDD:350350	89/151 (59%)
Ptp4a1	NP_035330.1	PTP-IVa1	1..167	CDD:350513	94/160 (59%)
		Interaction with ATF5. /evidence=ECO:0000269|PubMed:11278933	97..132		28/34 (82%)
		Phosphate binding. /evidence=ECO:0000250	105..110		4/4 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	139	1.000	Domainoid score	I4764
eggNOG	1	0.900	-	-		E1_KOG2836
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2587
Inparanoid	1	1.050	206	1.000	Inparanoid score	I3711
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54094
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001421
OrthoInspector	1	1.000	-	-		otm43989
orthoMCL	1	0.900	-	-		OOG6_101823
Panther	1	1.100	-	-	O	PTHR23339
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5007
SonicParanoid	1	1.000	-	-		X788
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.860