DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PRL-1 and ptp4a3

DIOPT Version :9

Sequence 1:	NP_001260487.1	Gene:	PRL-1 / 34952	FlyBaseID:	FBgn0024734	Length:	176	Species:	Drosophila melanogaster
Sequence 2:	NP_001135480.1	Gene:	ptp4a3 / 100216017	XenbaseID:	XB-GENE-943078	Length:	173	Species:	Xenopus tropicalis

Alignment Length:	167	Identity:	98/167 - (58%)
Similarity:	125/167 - (74%)	Gaps:	2/167 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 RPAPALIEYKGMKFLITDRPSDITINHYIMELKKNNVNTVVRVCEPSYNTDELETQGITVKDLAF 75
            ||||..:.||.|:||||..|::.|:|.:|.:|||....|||||||.:|:...||..||||.|..|
Frog     6 RPAPVEVCYKNMRFLITHNPTNATMNTFIEDLKKYGATTVVRVCEITYDKTPLEKDGITVMDWPF 70

  Fly    76 EDGTFPPQQVVDEWFEVLKDKYQQNPEACVAVHCVAGLGRAPVLVALALIELGLKYEAAVEMIRD 140
            :||..||.::||:|..:||.|:.::|..|||||||||||||||||||||||.|:|||.|::.||.
Frog    71 DDGAPPPNKIVDDWLNLLKTKFCEDPGCCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQ 135

  Fly   141 KRRGAINAKQLSFLEKYKPKARLKHK--NGHKNSCSV 175
            |||||||:|||::||||:||.||:.|  :.|||.|.:
Frog   136 KRRGAINSKQLTYLEKYRPKQRLRFKDPHNHKNKCCI 172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PRL-1	NP_001260487.1	PTP-IVa	10..163	CDD:350350	91/151 (60%)
ptp4a3	NP_001135480.1	PTP-IVa3	5..158	CDD:350511	91/151 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	136	1.000	Domainoid score	I4885
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	203	1.000	Inparanoid score	I3638
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001421
OrthoInspector	1	1.000	-	-		otm49162
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X788
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.050