Protein Alignment Ca-Ma2d and yfbK

DIOPT Version :10

• Sequence 1: NP_723955.2
• Gene: Ca-Ma2d / 34951
• FlyBaseID: FBgn0261999
• Length: 1215
• Species: Drosophila melanogaster
• Sequence 2: NP_416773.1
• Gene: yfbK / 946743
• ECOCYCID: G7177
• Length: 575
• Species: Escherichia coli
• Alignment Length: 608
• Identity: 130/608 - (21%)
• Similarity: 215/608 - (35%)
• Gaps: 208/608 - (34%)

  Fly    26 LLLLICGPHGGT------FPSTSIHWAEASAADEAVGKWATQFGDELFALAQKITKSQEIKEKYK 84
            |:|..|||....      .|||... .:..||.:|..|.|.|......||||     ||:    :
E. coli    14 LILSGCGPQPENKESQQQQPSTPTE-QQVLAAQQAAIKEAEQSAAAAKALAQ-----QEV----Q 68

  Fly    85 EYNARVELKNGTELIKSITKNVGRMLARKMDAVRCIQERAEYV-NENFEFNLTYALQNFTYFSSK 148
            :|:.:..|:             || |.......|..:.:|.:: |..               :::
E. coli    69 QYSDKQALQ-------------GR-LQEAPTFARAAKAKATHIANPG---------------TAR 104

  Fly   149 YSTFNGNSSEELEPNE-AEFA-----WMYRNME--LN------PDTHFYNTPVDTEHSSVHVPSN 199
            |..|:.|..:::..|. |.|:     ..|.|:.  ||      ||.      |..|....:.||:
E. coli   105 YQQFDDNPVKQVAQNPLATFSLDVDTGSYANVRRFLNQGLLPPPDA------VRVEEIVNYFPSD 163

  Fly   200 IWDRSERVLKTIMWSEHLDEVFRQNYQSDPALSWQYFGSDTGILRHYPAAQWTDTRPNRDDADTY 264
             ||..::  ::|..|:.:.  |...|:..|                   |.|.:.|.
E. coli   164 -WDIKDK--QSIPASKPIP--FAMRYELAP-------------------APWNEQRT-------- 196

  Fly   265 DCRKRSWYIETATCSKD----------IVILLDHSGSM-TGFRHHVAKFTIRSILDTFSNNDFFT 318
                   .::....:||          :|.|:|.|||| :..|..:.:.:::.::......|...
E. coli   197 -------LLKVDILAKDRKSEELPASNLVFLIDTSGSMISDERLPLIQSSLKLLVKELREQDNIA 254

  Fly   319 ILRYSSEVNDIIPCFNGALVQATPENIEVFNQQIEQLD---DPEGYANLTLAYETAFQLLRKYYD 380
            |:.|:.:....:|..:|:      ...|: |..|:.||   ...|.|.|.|||:.|.:...|...
E. coli   255 IVTYAGDSRIALPSISGS------HKAEI-NAAIDSLDAEGSTNGGAGLELAYQQATKGFIKGGI 312

  Fly   381 SRHCVTNSTCNQAIMLVTDGVAGNTTEVFQKYNWG-------------NGENGTSQMDTRVFTYL 432
            :|           |:|.|||          .:|.|             ..|:|.:     :.|:.
E. coli   313 NR-----------ILLATDG----------DFNVGIDDPKSIESMVKKQRESGVT-----LSTFG 351

  Fly   433 LG----KEVTKVREIQWMACLNRGYYSHVQTLDE----VHEEVLKYVDVIATPLVLQNEQHPPTW 489
            :|    .|...||    :|.:..|.||::.||.|    ::.|:.:.:..:|..:..|.|.: |.|
E. coli   352 VGNSNYNEAMMVR----IADVGNGNYSYIDTLSEAQKVLNSEMRQMLITVAKDVKAQIEFN-PAW 411

  Fly   490 THAFTDKTYDPKTSNEKRPRLMISVGVPAFDRFYRHANSTNPRARLLGVAGTDVPVEDIDKLTLP 554
            ...:....|      ||| :|.:           .|.|:.|..|..:| ||..:        ||.
E. coli   412 VTEYRQIGY------EKR-QLRV-----------EHFNNDNVDAGDIG-AGKHI--------TLL 449

  Fly   555 YKLGVNGYSFVVSNNGYVLLHPD 577
            ::|.:||....:....|.   ||
E. coli   450 FELTLNGQKASIDKLRYA---PD 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ca-Ma2d	NP_723955.2	VWA_N	124..251	CDD:462464	26/141 (18%)
		vWA_VGCC_like	267..461	CDD:238740	48/224 (21%)
		HK_sensor	547..669	CDD:365792	8/31 (26%)
		VGCC_alpha2	772..>999	CDD:462488
yfbK	NP_416773.1	YfbK	110..430	CDD:441879	85/420 (20%)
		DUF3520	392..569	CDD:432277	25/109 (23%)