Protein Alignment Ca-Ma2d and cachd1

DIOPT Version :9

• Sequence 1: NP_001260486.1
• Gene: Ca-Ma2d / 34951
• FlyBaseID: FBgn0261999
• Length: 1215
• Species: Drosophila melanogaster
• Sequence 2: XP_001334829.3
• Gene: cachd1 / 794807
• ZFINID: ZDB-GENE-100819-3
• Length: 1290
• Species: Danio rerio
• Alignment Length: 1027
• Identity: 212/1027 - (20%)
• Similarity: 364/1027 - (35%)
• Gaps: 302/1027 - (29%)

  Fly    25 LLLLLICGPHGGTFPSTSIHWAEASAADEAVGKWATQFGDELFALAQKITKSQE--IKEKYKEYN 87
            ||:...||..|..        :|.|..:||          ::.|:..|...:||  :....:.:|
Zfish    37 LLVFACCGFCGAD--------SEFSILEEA----------QVLAVQMKKLSTQELGVLTMQRIFN 83

  Fly    88 ARV---ELKNGTELIKSITKNVGRMLARKMDAVRCIQERAEYVNENFEFNLT---YALQNFTYFS 146
            :.|   :..||...::.:.|.:.....|.:|.|   ....:.|..::..:||   .|:|:.....
Zfish    84 SFVYTEKTSNGETEVQQLAKKIREKFNRYLDVV---NRNKQVVEASYTAHLTSPLTAIQDCCSIP 145

  Fly   147 SKYSTFNGN---------SSEELEP--NEAEFAWMYRNMELNPDTHFYNTPVDTEHSSVHVPSNI 200
            .....|:||         |.:.|.|  |...|         ||
Zfish   146 PSMMEFDGNFNANVSKTVSCDRLSPTVNSRAF---------NP---------------------- 179

  Fly   201 WDRSERVLKTIMWSEHLDEVFRQNYQSDPALSWQYFGSDTGILRHYPAAQWTDTRPNRDDADTYD 265
                         ...|:.|...|.:|:|.:.||||.|:.||...:||.::       ....|::
Zfish   180 -------------GRDLNSVLADNLKSNPGIKWQYFSSEEGIFTLFPAHKF-------HCKGTFE 224

  Fly   266 CRKRSWYIETA-TCSKDIVILLDHSGSMTGFRHHVAKFTIRSILDTFSNNDFFTILRYSSEVN-- 327
            .|.|..|:... ..||.||:::||..|:|..:..:|:.....||::...:|..::|..:..|.
Zfish   225 HRSRPVYVAAVRPQSKHIVVIIDHGASVTETQLQIARDAALVILNSIDEHDKISVLTIADTVRSC 289

  Fly   328 DIIPCFNGALVQATPE---NIEVFNQQIEQLDDPEGYANLTLAYETAFQLLRKYYDSRHCVTNST 389
            .:..|:...|..||.|   .:..|...|:..|....:|   :.::.||||||...:....:||:
Zfish   290 SLDQCYKSFLSPATSETKRKMSTFISNIKASDSSTQHA---VGFQKAFQLLRNTSNVTRQLTNT- 350

  Fly   390 CNQAIMLVTDGVAGNTTEVFQK---YNWGNGENGTSQMDTRVFTY-LLGKEVTKVREIQWMACLN 450
             :..|:.::.|:....:...:|   .:....||........:.|| |:...||.::|:.::.
Zfish   351 -DMMIIYLSSGITSRDSSEHEKRATLSAVKEENRHLNNSVMILTYALMNDGVTGLKELAFLR--- 411

  Fly   451 RGYYSHVQTLDEVHEEVLKY--VDVIATP------LVLQNEQHPPTWTHAFTDKTYDPKTSNEKR 507
                      |...:..|||  .|..|.|      :||....:..|....|....
Zfish   412 ----------DLAEQNSLKYGVQDRSALPVVKGSMMVLNQLSNLETTVGRFYINL---------- 456

  Fly   508 PRLMISV---GVPAFDRFYRHANSTNPRA-----RLLGVAGTDVPVEDIDKLTLPYKLGVNGYSF 564
            |..||.|   .:|..|:.......|..|.     .||||.|.||.:..|.:....|:..:..|:|
Zfish   457 PNRMIDVATFSLPYADQMGDGFIMTVSRPCYFGNLLLGVVGVDVNLAYILEDVTYYQDSLASYTF 521

  Fly   565 VVSNNGYVLLHPDL-RP-IGTNGKMNPNYNSIDFTEVEHLFEDQSPREPGESI-------LHIRN 620
            ::.|.||.|:||.| || :.|...::        |::.| :|:    .||..:       |.:.:
Zfish   522 LIDNKGYTLMHPSLTRPYLMTEAPLH--------TDIIH-YEN----IPGFPVVRQNILSLPLGS 573

  Fly   621 AMVRHEANEFKSISVKFHYDKMRRVSEEKQD--YFFAPLPNTPFTLGIVMPSEYGKTWIKVGEEV 683
            .::....|.    |:.:|.:::|..:.:..:  |.:..:.:|.|.|.||        :::....|
Zfish   574 QVIAVPVNS----SLSWHMNRLRDPNRDAYNVSYAWKLVQDTSFILCIV--------YVQPEIPV 626

  Fly   684 DKNKHMKINISDFFIGENWKVHPDWVYCKYHYLE-------------------------GHEFKT 723
            .:.|::....|...:              ||.|:                         ...|.:
Zfish   627 KQLKNLNTAPSSKLL--------------YHRLDLLGQPSSCLHFKQLATVESPTVMLSAGSFSS 677

  Fly   724 PEAELREFLAKMQNDWKWSEQYAEDESDWDDKDDLNCGRKTLGDDAYYCNKELVNLLIFDAKVTN 788
            |...|.:...|     :..|.|....|| :.:...|.|.|:          .:.|.::..:.||
Zfish   678 PYEHLSQPETK-----RMVEHYTAYLSD-NTRLIANPGLKS----------SVRNEVMATSHVT- 725

  Fly   789 SSYGVWRFESDEERQLIERFRADL----RFVATMSGLTRWQFIFGEVEVDTDREFGDYHTTAIDE 849
                      ||...|:|....:.    |::||.:|:.|   |:.          |.....|.|.
Zfish   726 ----------DEWMSLMEMSSLNCYIVRRYIATPNGVLR---IYP----------GSLMDKAFDP 767

  Fly   850 T---WYKSAILQHHEDRAESFVYSVKYYDDPMEDSEVKVTASHAIFPRDGGKEAPA--------- 902
            |   ||..|:.     ......::..|.|  :..:...||.||.|       .||:
Zfish   768 TRRQWYLHAVA-----NPGLITFTGPYLD--VGGAGYVVTISHTI-------HAPSSQMASGYTV 818

  Fly   903 CVVGFQFSHARMWERFFNITAVDHCNHCLPICTDD---DVDCVVIDNNAYIV 951
            .|:|..|:     .|:|....:|    .||||..|   .:.|.::::..|:|
Zfish   819 AVMGIDFT-----LRYFYKVLLD----LLPICNQDKGNKIRCFIMEDRGYLV 861

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ca-Ma2d	NP_001260486.1	VWA_N	124..251	CDD:285584	29/140 (21%)
		vWA_VGCC_like	267..461	CDD:238740	45/203 (22%)
		Cache_1	510..587	CDD:280839	28/86 (33%)
cachd1	XP_001334829.3	VWA_N	102..217	CDD:285584	33/161 (20%)
		vWFA	226..>355	CDD:294047	34/133 (26%)
		Cache_1	469..536	CDD:280839	21/66 (32%)
		Cache_1	785..866	CDD:280839	23/95 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2353
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810