Protein Alignment Ca-Ma2d and tag-180

DIOPT Version :9

• Sequence 1: NP_001260486.1
• Gene: Ca-Ma2d / 34951
• FlyBaseID: FBgn0261999
• Length: 1215
• Species: Drosophila melanogaster
• Sequence 2: NP_001022363.1
• Gene: tag-180 / 174730
• WormBaseID: WBGene00007041
• Length: 1067
• Species: Caenorhabditis elegans
• Alignment Length: 1264
• Identity: 252/1264 - (19%)
• Similarity: 458/1264 - (36%)
• Gaps: 342/1264 - (27%)

  Fly     9 MTHFAVILTAFSFSQPLLLLLICGPHGGTFPSTSIHWAEASAADEAVGKWATQFGDEL---FALA 70
            |.:..|:|...|.||              .|..:|..|.||.|         ||...:   |...
 Worm     1 MGYVHVVLFWLSLSQ--------------LPVDTIEEAPASIA---------QFSANILRDFETQ 42

  Fly    71 QKITKSQEIKEKYKEYNARVELKNGTELIKSITKNVGRMLARKMDAVRCIQERAEYVNENFEFNL 135
            .:.:..||..||.|. :.:.:.::..|.::..|:::.|::..::||::.:...||.....|:
 Worm    43 SRFSLVQEEFEKLKP-DIKSKKEDAAEKLRVATEHLDRLVTNRVDALKKLASSAEASAAVFD--- 103

  Fly   136 TYALQNFTYFSSKYSTFNGNSSEELEPNEAEFAWMYRNMELNPDTHFYNTPVDTEHSS---VHVP 197
                   .|....|:....:...|        |:|.:..|  .|.||.:..|  ||:|   :|:.
 Worm   104 -------EYDDQAYAVPQADKRCE--------AYMKKMNE--SDMHFVSNMV--EHNSKSGIHIT 149

  Fly   198 SNIWDRSERVLKTIMW--SEHLDEVFRQNYQSDPALSWQYFGSDTGILRHYPAAQWTDTRPNRDD 260
            ...:....||::...|  ::||::....|.:..|.:..||.|:.:|:.|.||...| ...|....
 Worm   150 VESYQCDPRVMRDFDWTGTKHLEKTMSDNKEKAPEMGHQYIGTYSGLTRMYPRRHW-KVEPTPIT 213

  Fly   261 ADTYDCRKRSWYIETATCSKDIVILLDHSGSMTGFRHHVAKFTIRSILDTFSNNDFFTILRYSSE 325
            .|.:|.|.|.|::...:..||||.|||:|||:.|...|:.|.|:..||.|.|.||:|..:.:::.
 Worm   214 IDLFDPRFRPWFVNAESVPKDIVFLLDYSGSVKGPTMHLIKITMMYILSTLSPNDYFFGVYFNNH 278

  Fly   326 VNDIIPCFNGALVQATPENIEVFNQQIEQLDDPEGYANLTLAYETAFQLLRKYYDSRHCV---TN 387
            .|.||.|.|...:.||..|.:||.:::..|::.: .|:.....:.:..:||...||...:   ..
 Worm   279 FNPIISCANRTFMPATTSNKKVFFEELGMLEEKD-QAHFATPLKFSLDVLRGNLDSNQSLFADYR 342

  Fly   388 STCNQAIMLVTDGVAGNTTEVF-QKYNWGNGENGTSQMDTRVFTYLLGKEVTKVREIQWMACLNR 451
            |..::.:::.||||.....::. :::...|.|.      .|:|.:.:|...:.:...|:|||.:.
 Worm   343 SEGHKLLIIFTDGVDEWPHQILDEEFQTRNSEL------IRIFGFSMGYGTSLLPLQQYMACKSH 401

  Fly   452 GYYSHVQTLDEVHEEVLKYVDVIATPLVLQN---------------EQHPPTWTHAFTDKTYDPK 501
            |.||.:.::          :||......:||               |:..|:||..:.:
 Worm   402 GGYSEIDSI----------MDVKPQSRTIQNVLSQVRGDELKGTNAEKREPSWTQLYME------ 450

  Fly   502 TSNEKRPRLMISVGV-PAFDRFYRHANSTNPRARLLGVAGTDVPVEDIDKLTLPYKLGVNGYSFV 565
             :....|.:.:|:.: .:..|.:|.       .:|.||...|:.:::..| .||.. ....|.::
 Worm   451 -TQGTGPIVTLSLPILTSEQRIWRD-------QKLAGVVAIDISIKEFTK-HLPTS-SEQMYGYI 505

  Fly   566 VSNNGYVLLHPDLRPIGTNGKMNPNYNSIDFTEVEHL-----FEDQSPREPGESILHIR----NA 621
            |.|||.::.||.|:              |..|||..:     ::.|..::...|.|.:.    :.
 Worm   506 VDNNGMLIYHPQLQ--------------IPKTEVHCVRRSACYDAQQVKQKAGSGLRVHYGFSDE 556

  Fly   622 MVRHEANEFKSISVKFHYD---------KMRR-----------VSEEKQDYFFAPLPNTPFTLGI 666
            .|........||.....||         .:||           :.:..::|..:.:.::||||.|
 Worm   557 RVYRLVGLIDSIPTLDMYDLEGDSTAIRDLRRRITTKTCYEEAIKDNSKEYHCSHIKDSPFTLVI 621

  Fly   667 VMPSEYGKTWIKVGEEVDKNKHMKINISDFFIGENWKVHPDWVYCKYHYLEGHEFKTPEAELREF 731
            |...:.            |..:...::.:..:.:|..|               .|..|..::.:
 Worm   622 VNNIQL------------KTVYYDDSVQELGLTDNKLV---------------TFFYPRRDVCQ- 658

  Fly   732 LAKMQNDWKWSEQYAEDESDWDDKDDLNCGRKTLGDDAYYCNKELVNLLIFDAKVTNSSYGVWRF 796
                   ||..|..|.|.                                         :.||..
 Worm   659 -------WKLDEYAAHDR-----------------------------------------FRVWSD 675

  Fly   797 ESDEERQLIERFRADLRFVATMSGLTRWQFIFGEVEVDTDREFGDYHTTAIDETWYKSAILQHHE 861
            .|::|....:..|....|.   .||..|...:.:.:::        |||.:...:.::|.:.|:
 Worm   676 ISEKEICAQDDMRLPRAFT---KGLGSWTQSWPKSDIE--------HTTCLLAQYPENASVPHY- 728

  Fly   862 DRAESFVYS----VKYYD----------DPMEDSEVKVTASH----------------AIFPRDG 896
              ..|||::    ..:|.          :...|.|:|:|.::                .|...|.
 Worm   729 --VNSFVHTRSKLTAFYPTCSSHDMKAVNKKFDEEIKLTDNNDFVQFSMRSESLLIYRTIADYDN 791

  Fly   897 GKEAPACVVGFQFSHARMWERFFNITAVDHCNHCLPICTDDDVDCVVIDNNAYIVIGQNINTTGK 961
            .:.|   |||.|:......:.|.|.|   ..|....||...  :|.:|..|.: ||..:.:....
 Worm   792 NRLA---VVGTQWKENFFDQYFDNFT---RQNPDWKICRKQ--ECSIITRNGH-VIASSAHRAPA 847

  Fly   962 FFGEFHGDVMTAMVERGIFLSIEVYDYQEQCKEEPKA--GSDGHGLLHPLRLLSLGWKYLVGRLF 1024
            ...:|...:..::|:..:..:....:.|.:||.:..|  .|...|....||       |.|..:
 Worm   848 HLAKFDPQLFESLVKVNLVSTNSWTEVQSECKAKRVAPWSSAAPGSSSILR-------YFVTSI- 904

  Fly  1025 FEYQRIQWWADGAPFMEYTDEIEDEYVAVGDGGKSSASKPKDDSDDENAMFDEPEPDPIYKAC-- 1087
            |:..:..:|.:          :.:..:.:.|...|...        ....|.:.:|   ::.|
 Worm   905 FKLAKTSFWRN----------LLESALTLVDAQPSMTG--------NTCTFQKIKP---FERCFM 948

  Fly  1088 ---DKRSTLYALQPSALVGINDFVEAPSTRPFLVKKIPNSNLVLVVVNVLMPSRSVRLTTEPQRM 1149
               ..|.||...:...|.|::.........|     :|::.|.|::.
 Worm   949 KFFHYRMTLNITKQLQLTGMSTCSRYAKLYP-----VPHTTLSLIIA------------------ 990

  Fly  1150 EYDKEFPCYKLNMSF-YERRRIEECYTVH 1177
              |:....|:....| .|.|::|:|..||
 Worm   991 --DRACSQYRPKRIFESEPRKLEKCDVVH 1017

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ca-Ma2d	NP_001260486.1	VWA_N	124..251	CDD:285584	31/131 (24%)
		vWA_VGCC_like	267..461	CDD:238740	57/197 (29%)
		Cache_1	510..587	CDD:280839	18/77 (23%)
tag-180	NP_001022363.1	VWA_N	<106..201	CDD:369855	25/106 (24%)
		vWA_VGCC_like	220..411	CDD:238740	57/207 (28%)
		dCache_1	<430..>517	CDD:376917	21/102 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	63	1.000	Domainoid score	I6824
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000496
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10166
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010