Protein Alignment Ca-Ma2d and stj

DIOPT Version :10

• Sequence 1: NP_723955.2
• Gene: Ca-Ma2d / 34951
• FlyBaseID: FBgn0261999
• Length: 1215
• Species: Drosophila melanogaster
• Sequence 2: XP_061499939.1
• Gene: stj / 1276178
• VectorBaseID: AGAMI1_003828
• Length: 1290
• Species: Anopheles gambiae
• Alignment Length: 1349
• Identity: 470/1349 - (34%)
• Similarity: 670/1349 - (49%)
• Gaps: 244/1349 - (18%)

  Fly    16 LTAFSFSQPLLLLLICGPHGGTFPSTSIHWAEASAADEAVGKWATQFGDELFALAQKITKSQEIK 80
            :.||:|   ||...|........|:|:|.:       ..|..||.:.|.||:.|...||:.:|::
Mosquito    12 ILAFTF---LLFFAISITRSADEPTTTIKY-------NVVQAWAAKLGGELWHLGDFITRRKEVE 66

  Fly    81 EKYKEYNARVELKNGTELIKSITKNVGRMLARKMDAVRCIQERAEYVNENFEFNLTYALQNFTYF 145
            |.:|:  |:|..|||.::::.:.|::..|:..|:.||:.|.:.||  |....|:.....|:|.|:
Mosquito    67 ESFKQ--AQVVNKNGAKIVEEMAKDLKYMMDAKVSAVKRIMDTAE--NTAISFDEEPVNQSFQYY 127

  Fly   146 SSKYSTFNGNSSEELEPNE-------------AEFAWMY--RNMELNPDTHFYNTPVDTEHSSVH 195
                     |:.:.:||.|             |:.....  :.:.|....||:|..|:|..||||
Mosquito   128 ---------NAKQMIEPGEIITTPIPMIDEDPADITTPIPPKEIVLTKKRHFFNEAVNTTVSSVH 183

  Fly   196 VPSNIWDRSERVLKTIMWSEHLDEVFRQNYQSDPALSWQYFGSDTGILRHYPAAQWTDTRPNRDD 260
            ||:|::||:..|:|.|.|||.||.:|..||..||.|:||||||.:|.||.:||.:|     .:|.
Mosquito   184 VPTNVYDRATEVIKAIKWSEALDSIFYNNYIGDPTLTWQYFGSSSGFLRQFPATKW-----EQDP 243

  Fly   261 ADTYDCRKRSWYIETATCSKDIVILLDHSGSMTGFRHHVAKFTIRSILDTFSNNDFFTILRYSSE 325
            .|.||||.||||||.|...||::||:|.||||||.|..:||..:.:||||...||:..|..:|.|
Mosquito   244 VDLYDCRLRSWYIEAANSPKDMLILVDSSGSMTGQRKDIAKHVVSNILDTLGPNDYVNIFTFSEE 308

  Fly   326 VNDIIPCFNGALVQATPENIEVFNQQIEQLDDPEGYANLTLAYETAFQLLRKYYDSRHCVTNSTC 390
            |.:::|||...||||...||......::.::..| .||::.|...||:||.::.::|:   .:.|
Mosquito   309 VAEVVPCFRDTLVQANMGNIRELKLGMDNIETNE-IANVSAALTRAFELLEQFRETRN---GARC 369

  Fly   391 NQAIMLVTDGVAGNTTEVFQKYNWGNGENGTSQMDTRVFTYLLGKEVTKVREIQWMACLNRGYYS 455
            |||||||:|||..:..|||:::||    .....:..||||||:|:||..|:||:.|||.|:|||.
Mosquito   370 NQAIMLVSDGVPYSFDEVFEQFNW----KELPFIPVRVFTYLIGREVADVKEIKEMACRNQGYYV 430

  Fly   456 HVQTLDEVHEEVLKYVDVIATPLVLQNEQHPPTWTHAFTDKTYDPKT------------------ 502
            |:.|:.||.||||.|:.|||.||||...:||..|:..:.| ..|||.
Mosquito   431 HLSTMAEVREEVLNYIPVIARPLVLNKREHPVVWSEIYAD-VEDPKMTDWLWEIKERAEQKERFI 494

  Fly   503 ------------------------------SNEKRPRLMISVGVPAFDRFYRHANSTNP------ 531
                                          ||.::...|.:|.||.||| ..:||.|..
Mosquito   495 DYRKNRVLFYSPEEQHRRMIMKQRMNQDPYSNTQKYNFMTTVSVPVFDR-RENANITEDILMNEA 558

  Fly   532 ----------RARLLGVAGTDVPVEDIDKLTLPYKLGVNGYSFVVSNNGYVLLHPDLRPIGTNGK 586
                      .|.:|||||.|||:.:|.|...|:.||||||:|:|:||||:|.|||.||: ....
Mosquito   559 YWVTITRETRVANILGVAGADVPIAEIKKYLKPHLLGVNGYAFIVTNNGYILTHPDFRPV-FQDI 622

  Fly   587 MNPNYNSIDFTEVEHLFEDQSPREPGESILHIRNAMVRHEANEFKSISVKFHYDKMRRVSEEKQD 651
            :.|.||::|..|||...:||.|||....:|::|.::: :::...|.|.||:|:|:|:|||..|:.
Mosquito   623 LKPAYNTVDMIEVELTDDDQGPREFNNQLLNMRESII-NQSTGAKWIRVKYHFDEMKRVSRTKRQ 686

  Fly   652 YFFAPLPNTPFTLGIVMPSEYG--KTWIKVGEEVDKNKHMKINISDFFIGENWKVHPDWVYCKYH 714
            |::.|:.||||||.:..|..||  :..|:..:|:.:......|::.||.|.|||:||||||||
Mosquito   687 YYWTPIKNTPFTLVVTYPETYGLNRLQIRTEDEIHRIHAKGSNVASFFTGNNWKIHPDWVYCK-- 749

  Fly   715 YLEGH---EFKTPEAELREFLAKMQ-NDWKWSE----------QYAEDESDWDDKDDLNCGRKTL 765
            ||..|   .|.|||.||:.||.:|: ..|||..          .::.......||
Mosquito   750 YLNEHPNETFATPELELKHFLERMKLGGWKWPSNRTPPPPEHAMFSNITGKLPDK---------- 804

  Fly   766 GDDAYYCNKELVNLLIFDAKVT-------NSSYGVWRFESDEE--------------RQLIERFR 809
              |.|||::.|:..|::|||||       :.|.|    ..||:              .:..:||.
Mosquito   805 --DYYYCDRGLMQALVYDAKVTEWFSKNVSGSGG----NKDEKGPSPIAVLMGLLPRNEFKQRFG 863

  Fly   810 ADLRFVATMSGLTRWQ-FIFGEVE-VDTDREFGDYHTTAIDETWYKSAILQHHEDR--------- 863
            ..:.|:||.||||||| :..|..| ...:.:|.:.|..||||.|||.|:..::.:|
Mosquito   864 ITVSFLATHSGLTRWQEYATGADESKQAEPDFSETHNRAIDEVWYKRAVELYYSNRNRKGADGEN 928

  Fly   864 ------AESFVYSVKYYDDPMEDSEVKVTASHAIFPRDGGKEAPACVVGFQFSHARMWERFFNIT 922
                  ..||||||.:  |....::..||||||||..||.:|||..||||||.|:.::..|.|||
Mosquito   929 GKDDSDRNSFVYSVPF--DAGNRNDTLVTASHAIFHADGAREAPVAVVGFQFHHSALYTLFKNIT 991

  Fly   923 AVDHCNH----CLPICTDDDVDCVVIDNNAYIVIGQNINTTGKFFGEFHGDVMTAMVERGIFLSI 983
            :  .|.|    |...|...|..|.|||||.::||.:.:..||.||||.....|..:::..||.::
Mosquito   992 S--QCGHGDPRCEKTCFTGDYQCYVIDNNGFVVISEQLQETGAFFGEVKPAFMQRLLDDSIFRNV 1054

  Fly   984 EVYDYQEQCKEEPKAGSDGHGLLHPLRLLSLGW-------KYLVGRLFFEYQRIQWWADGAPFME 1041
            .|||||..|.....:.:.|..|..|||||   |       .|||            |.....|:.
Mosquito  1055 TVYDYQAVCFMAKGSINLGTVLQTPLRLL---WWLLTNTFSYLV------------WVVMQLFLS 1104

  Fly  1042 YTDEIEDEYVAVGDGGKSSASKPKDDSDDENA-MFDEPE----------PDPIYKACDKRSTLYA 1095
            .....::.|    |.|.........|.||... .:.|||          |:|    ||...|||.
Mosquito  1105 LARAYDEMY----DTGAYDVVPELGDLDDPTLNRYKEPEFNKVLINRTRPEP----CDHVITLYE 1161

  Fly  1096 LQPSALVGINDFVEAPSTRPFLVKKIPNSNLVLVVVNVL--MPSRSVRLTTEPQRMEYDKEFPCY 1158
            |.......:.........||::|..||:|||:|:|::.|  :|:...:|:|.|...:|:....|:
Mosquito  1162 LNMDVDPSVYTKEAHQCERPYVVLPIPSSNLLLLVLDTLCPLPTHVPQLSTWPVEHDYNASLACH 1226

  Fly  1159 KLNMSFYERRRIEECYTVHEDEELYTYCGNASRLVLTLQLMPLTIILVF 1207
            |.......|||...|...|.:|.:...||:.|  :..|.:..|..:|.|
Mosquito  1227 KARSDPLPRRRPLTCINKHANESVIELCGDGS--IPRLNVALLLALLAF 1273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ca-Ma2d	NP_723955.2	VWA_N	124..251	CDD:462464	52/141 (37%)
		vWA_VGCC_like	267..461	CDD:238740	87/193 (45%)
		HK_sensor	547..669	CDD:365792	54/121 (45%)
		VGCC_alpha2	772..>999	CDD:462488	96/268 (36%)
stj	XP_061499939.1	None