DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Ca-alpha1D and SCN4A

DIOPT Version :9

Sequence 1:NP_723952.2 Gene:Ca-alpha1D / 34950 FlyBaseID:FBgn0001991 Length:2705 Species:Drosophila melanogaster
Sequence 2:NP_000325.4 Gene:SCN4A / 6329 HGNCID:10591 Length:1836 Species:Homo sapiens


Alignment Length: Identity:/ - (0%)
Similarity:/ - (0%) Gaps:/ - (0%)


- Green bases have known domain annotations that are detailed below.


Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ca-alpha1DNP_723952.2 Ion_trans 767..1042 CDD:395416
Ion_trans 1137..1379 CDD:395416
Ion_trans 1496..1809 CDD:395416
Ion_trans 1851..2126 CDD:395416
GPHH 2135..2188 CDD:407139
Ca_chan_IQ 2199..2271 CDD:400901
SCN4ANP_000325.4 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 39..63
I. /evidence=ECO:0000305 113..454
Ion_trans 152..457 CDD:278921
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 493..530
II. /evidence=ECO:0000305 560..832
Ion_trans 595..790 CDD:278921
Na_trans_assoc 816..1026 CDD:284034
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 863..886
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 930..992
III. /evidence=ECO:0000305 1013..1326
Ion_trans 1048..1304 CDD:278921
Na_channel_gate 1296..1348 CDD:240441
Important for rapid channel inactivation. /evidence=ECO:0000250|UniProtKB:P15390 1310..1312
IV. /evidence=ECO:0000305 1335..1633
Ion_trans 1370..1609 CDD:278921
GPHH 1620..1675 CDD:293510
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1778..1836
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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