DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ca-alpha1D and F17C8.6

DIOPT Version :9

Sequence 1:	NP_723952.2	Gene:	Ca-alpha1D / 34950	FlyBaseID:	FBgn0001991	Length:	2705	Species:	Drosophila melanogaster
Sequence 2:	NP_497974.1	Gene:	F17C8.6 / 175626	WormBaseID:	WBGene00008911	Length:	279	Species:	Caenorhabditis elegans

Alignment Length:	249	Identity:	50/249 - (20%)
Similarity:	89/249 - (35%)	Gaps:	52/249 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly  2115 MDNFD--YLTRDWSILGPHHLDEFIRLWSEYDPDAKGRIKHLDVVTLLRKI---------SPPLG 2168
            |:||.  |.:.:.::|....:..|..:|:..|.:.|..|....|..|||.:         |..|.
Worm     1 MENFSLLYSSEEDALLSYADIRNFQLVWNMVDIEQKRSIPVRRVKFLLRLLKGRLEVNDESDGLL 65

  Fly  2169 FGKLCPHRMACKRLVSMNMPLNSDGTVLFNATLFAVVRTSLSIKTDGNIDD--ANSELRATI-KQ 2230
            |..:| |.|.         .|::...|.|:..|..:...|:.|:....:::  ...||...| ::
Worm    66 FKHMC-HEME---------RLHNGDDVSFHDVLNMLSYRSVDIRKSLQLEELLQREELEYIIEEE 120

  Fly  2231 IWKRTNPKLLDQVVPPPGNDDEVTVGKF------YATYLIQDYFRR----FKKRKEQEGKEGHPD 2285
            :.|.|....|:..:.........|:||.      :|....|:...:    .:...|::..:|...
Worm   121 VAKHTIRAWLENCLKNIKAKQNNTLGKMSSIGSTFAFPQSQEVLTKGVVLTEASPEEDSLQGDKG 185

  Fly  2286 SNTVTLQAGLRTLHEVSPALKRAIS------------------GNLDELDQEPE 2321
            |.....|.|......|:.|.|:::.                  |..|||::..|
Worm   186 SGKKKAQRGNSITEIVAEAQKKSVKRATDKISERRGTLRQMQMGTYDELEEVEE 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ca-alpha1D	NP_723952.2	Ion_trans	767..1042	CDD:395416
		Ion_trans	1137..1379	CDD:395416
		Ion_trans	1496..1809	CDD:395416
		Ion_trans	1851..2126	CDD:395416	4/12 (33%)
		GPHH	2135..2188	CDD:407139	15/61 (25%)
		Ca_chan_IQ	2199..2271	CDD:400901	14/84 (17%)
F17C8.6	NP_497974.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D172471at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010