DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment beat-Ia and beat-VI

DIOPT Version :9

Sequence 1:	NP_001285975.1	Gene:	beat-Ia / 34947	FlyBaseID:	FBgn0013433	Length:	437	Species:	Drosophila melanogaster
Sequence 2:	NP_001263035.1	Gene:	beat-VI / 43377	FlyBaseID:	FBgn0039584	Length:	332	Species:	Drosophila melanogaster

Alignment Length:	275	Identity:	90/275 - (32%)
Similarity:	135/275 - (49%)	Gaps:	32/275 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 ALTTILLALTLEMTAALRDVRVRVPHAVRRSEKAILKCFYDIEDDSLYSVKWYKGRREFYRYTPK 75
            ||:.|:::..|.....|:|:::.||.||.....|.|.|.||:|..:||:|:||.|:.|||||.|:
  Fly    36 ALSWIIISELLLSAHCLKDLKIFVPEAVLMGNAATLSCQYDLEQAALYAVRWYFGQEEFYRYVPR 100

  Fly    76 ETPPMKVFHFPGVKVRRVSSNESQVVLDAVTMATSGKYSCEVSADAPSFHTLIAAAELEVIETPH 140
            |..|..||...|:.|...:|:.:.|.|..||...||.|.||||.|||.|||.|.:|.::|||.|.
  Fly   101 EAKPTFVFAVAGINVDLANSDATSVTLKGVTRELSGSYQCEVSEDAPLFHTEIRSAHMQVIELPK 165

  Fly   141 NAPFITGIRPRYRVGDILRGNCTSRHSRPAANLTWTVNNEEVNPALVRHHKILRDARNDMET--- 202
            :.|.:...:....|.|..:..||...|.|.||:||::|..::....::  :|.:|......|
  Fly   166 DDPVMQVDKKVIGVNDNFKAVCTVGPSYPPANITWSINGNQIRRTPLQ--RISQDTYEGSTTYSS 228

  Fly   203 --------AVVGIHFVVTDQHFDNGKLKLRCSAQLHDVYWKTTEKII---------LETDLFPKH 250
                    |:.|. |....||    .:.|:|...:..:|.|...:.|         :..:|....
  Fly   229 LDIYPNSQALQGF-FETKYQH----SVNLQCVVTIRHMYHKVVAQRIGLNAAPPTTISPNLLGLE 288

  Fly   251 GNG--ANGNHVNPDD 263
            |:.  |||   :||:
  Fly   289 GSKRYANG---DPDN 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
beat-Ia	NP_001285975.1	Ig	32..118	CDD:299845	38/85 (45%)
beat-Ia	NP_001285975.1	Ig	161..240	CDD:299845	21/89 (24%)
beat-VI	NP_001263035.1	Ig	66..142	CDD:416386	33/75 (44%)
		Ig strand B	67..76	CDD:409353	3/8 (38%)
		CDR1	76..83	CDD:409353	2/6 (33%)
		Ig strand C	83..91	CDD:409353	4/7 (57%)
		FR2	84..91	CDD:409353	3/6 (50%)
		CDR2	94..108	CDD:409353	7/13 (54%)
		Ig strand C'	94..99	CDD:409353	4/4 (100%)
		Ig strand C'	102..104	CDD:409353	0/1 (0%)
		FR3	109..143	CDD:409353	12/33 (36%)
		Ig strand D	117..121	CDD:409353	0/3 (0%)
		Ig strand E	123..127	CDD:409353	1/3 (33%)
		Ig strand F	136..144	CDD:409353	5/7 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000798
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR21261
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.010