Protein Alignment BicC and hdlbp

DIOPT Version :10

• Sequence 1: NP_476865.1
• Gene: BicC / 34946
• FlyBaseID: FBgn0000182
• Length: 905
• Species: Drosophila melanogaster
• Sequence 2: NP_001006854.1
• Gene: hdlbp / 448610
• XenbaseID: XB-GENE-942331
• Length: 1283
• Species: Xenopus tropicalis
• Alignment Length: 600
• Identity: 123/600 - (20%)
• Similarity: 223/600 - (37%)
• Gaps: 199/600 - (33%)

  Fly     6 SFNKLMYPSAADVAKPP------MVGLEVEAGSIG-SLSSLHALPSTTSVGS-GAPS-------- 54
            :..:::..:...|..||      .|.|..|...:| :|:.::|..::.:|.| .|||
 Frog   318 NLQEILERTGVSVEIPPSDSSSETVILRGEPEKLGQALTEVYAKANSFTVASVSAPSWLHRFIIG 382

  Fly    55 -------ETQSEISSVDSDWSDIRAIAMKLGVQNPDDLHTERFKVDRQKLEQLIK--------AE 104
                   :...:|..|..::::...   |:.::.|    ||...|.:|::|.|.:        ||
 Frog   383 KKGQNLAKITQQIPKVHIEFTEGED---KISLEGP----TEDVTVAQQQMEALFRDLISRMDFAE 440

  Fly   105 SSIE--------GMNGAEYFFHDIMNTTDTY-VSWPCRLKIGAKSKKDPHVRIVGKVDQVQRAKE 160
            .:|:        |.:||:     |....:.| ||    ::|...|:|..|:||.|....||:||:
 Frog   441 INIDHRFHRHLIGKSGAK-----INKIKEQYKVS----VRIPQDSEKSNHIRIEGDPQGVQQAKK 496

  Fly   161 RIL---SSLDSRGTRVIMKMDVSYTDHSYIIGRGGNNIKRIMDD-THTHIHFPDSNRSNPTEKSN 221
            .:|   |.:::..|:.::   :....|..|||:.|..|:.|.:. ....|:|||     |.:||:
 Frog   497 ELLELASRMENERTKDLI---IEQKFHRTIIGQKGERIREIREKFPEVIINFPD-----PAQKSD 553

  Fly   222 QVSLCGSLEGVERARALVR------------LSTPLLISFEMPVMGPNKPQPDHETPYIKMIETK 274
            .|.|.|....||:....::            :|.|:...|...::|.....       ||.|..:
 Frog   554 IVQLRGPKNEVEKCTKYLQKMVSELVENSYSISVPIFKQFHKNIIGKGGAN-------IKKIREE 611

  Fly   275 FNVQ-------------VIFSTRP----------------------------KLHTSLVLVK--- 295
            .|.:             ||...||                            |||.||:..|
 Frog   612 CNTKIDLPAENSNSEMIVITGKRPNCEAARDRILAIQKELANITELEVNIPSKLHNSLIGAKGRF 676

  Fly   296 ------------------GSEKESAQVRDATQLLINFACESIASQIL----------VNVQMEIS 332
                              ||..::..:|...|     ..|....|:|          ...:::..
 Frog   677 IRSIMEECGGVHIHFPSEGSGSDTVTIRGPVQ-----DVERAKKQLLQLAEEKQTKSFTSELKAK 736

  Fly   333 PQHHEIVKGKNNVNLLSIMERTQTKIIFPDLSDMNVKPLKKSQVTISGRIDDVYLARQQLLGNLP 397
            |::|:.:.||...|:..:.::|..:||||...|.:     :..:||.|..|.|..|:::
 Frog   737 PEYHKFLIGKGGGNIRKVRDQTGARIIFPTADDKD-----QQLITIVGTEDSVKEAQKE------ 790

  Fly   398 VALIFDFPDNHNDASEIMSLNTKYGVYITLRQKQRQSTLA-------------------IVVKGV 443
              |.|......|...:.||::.|:..:..:|:.|....:|                   :.:||.
 Frog   791 --LEFLIKSLDNIVEDSMSVDPKHHRHFVIRRGQVLRDIAEEYGGVIVSFPRSGVQSDRVTLKGA 853

  Fly   444 EKFIDKIYEARQEIL 458
            ::.::   .|:::||
 Frog   854 KECVE---AAKKKIL 865

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BicC	NP_476865.1	KH-I_BICC1_rpt1	85..166	CDD:411848	29/100 (29%)
		KH-I_BICC1_rpt2	171..240	CDD:411849	20/69 (29%)
		KH-I_BICC1_rpt3	325..393	CDD:411850	17/67 (25%)
		SAM_BICC1	805..868	CDD:188919
hdlbp	NP_001006854.1	KH-I_Vigilin_rpt1	78..145	CDD:411833
		KH-I_Vigilin_rpt2	148..222	CDD:411834
		KH-I_Vigilin_rpt3	225..286	CDD:411835
		KH-I_Vigilin_rpt4	298..359	CDD:411836	8/40 (20%)
		KH-I_Vigilin_rpt5	365..434	CDD:411837	15/75 (20%)
		KH-I_Vigilin_rpt6	436..503	CDD:411804	22/75 (29%)
		KH-I_Vigilin_rpt7	508..574	CDD:411838	20/73 (27%)
		KH-I_Vigilin_rpt8	584..645	CDD:411839	12/67 (18%)
		KH-I_Vigilin_rpt9	654..723	CDD:411840	13/73 (18%)
		KH-I_Vigilin_rpt10	727..792	CDD:411841	17/77 (22%)
		KH-I_Vigilin_rpt11	803..868	CDD:411842	10/65 (15%)
		KH-I_Vigilin_rpt12	876..970	CDD:411843
		KH-I_Vigilin_rpt13	972..1049	CDD:411844
		KH-I_Vigilin_rpt14	1053..1124	CDD:411845
		KH-I_Vigilin_rpt15	1126..1194	CDD:411846