DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment BicC and SPBC28E12.02

DIOPT Version :9

Sequence 1:	NP_476865.1	Gene:	BicC / 34946	FlyBaseID:	FBgn0000182	Length:	905	Species:	Drosophila melanogaster
Sequence 2:	NP_595755.1	Gene:	SPBC28E12.02 / 2540579	PomBaseID:	SPBC28E12.02	Length:	663	Species:	Schizosaccharomyces pombe

Alignment Length:	386	Identity:	71/386 - (18%)
Similarity:	137/386 - (35%)	Gaps:	87/386 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 IMNTTDTYVSWPCRLKIGAKSKKDPHVRIVGKVDQVQRAKERILSSLDSRGTRVIMKMDVSYTDH 184
            ||....:::.:|...|.|.::..             :.:|.:|.||..:...:..:::  :....
pombe   332 IMEENSSFIRFPEYFKEGGETSP-------------ENSKVKIYSSSIANSEKTALRL--AKLAS 381

  Fly   185 SYIIGRGGNNIKRIMDDTHTHIHFPDS-NRSNPTEK-------SNQVSLCGSL---EGVERARA- 237
            .|:.|:....:    :|....:....| .|::..||       |:.||..||:   .|:....:
pombe   382 KYVQGKTQFGV----EDNEDFLRVAGSWRRASTIEKGVSSSELSSIVSSTGSIVETNGIGEKMSF 442

  Fly   238 --LVRLSTPLLISFEMPVMGPNKPQPDHETPYIKMIETKFNVQVIFSTRPKLHTSLVLVKGSEKE 300
              |.:||.|                |......|.:|.....|:::      |.|:.:...|.|..
pombe   443 SPLKKLSIP----------------PTEFVAQIAIICMASGVEML------LKTNGIEYFGQENT 485

  Fly   301 SAQVRD-ATQLLINFACESIASQILVNVQMEISPQHHEIVKGKNNVNLLSIMERTQTKIIFPDLS 364
            .....| |:::...|. :|...|||    :|...:..:.:.||.|..|..:.::.:..:   ...
pombe   486 VPIAMDKASKIFYKFG-QSQWHQIL----LEAPTKDQDFISGKKNGKLDKVKQQCRFNL---KNG 542

  Fly   365 DMNVKPLKKSQVTI---SGRIDDVYLARQQLLGNLPVALIFDFPDN-HND-----ASEIMSLNTK 420
            |:...|...|..|:   |..::.|......:|...|..:.|..|:. |..     ..:|..:...
pombe   543 DILFCPQSTSIFTVDIYSDELERVIKGMNTMLLEFPAEMHFYVPEEIHKKLIGFRGEQIQRVTKL 607

  Fly   421 YGVYITLRQKQRQSTLA-------IVVKGVEKFIDKIYEARQEILRLATPFVKPEIPDYYF 474
            |..||..      ||..       ::::...||.:.::..|...::.|.. :..:||.|.|
pombe   608 YNSYIEF------STTPFDCYGHNVLIRTPSKFSENLWAVRSLFIKTAEG-LGYDIPKYLF 661

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BicC	NP_476865.1	vigilin_like_KH	174..240	CDD:239087	14/79 (18%)
		vigilin_like_KH	327..393	CDD:239087	11/68 (16%)
		SAM_BICC1	805..868	CDD:188919
		SAM	807..867	CDD:197735
SPBC28E12.02	NP_595755.1	COG5166	1..663	CDD:227495	71/386 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2208
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900