Protein Alignment BicC and vgl1

DIOPT Version :9

• Sequence 1: NP_476865.1
• Gene: BicC / 34946
• FlyBaseID: FBgn0000182
• Length: 905
• Species: Drosophila melanogaster
• Sequence 2: NP_588106.2
• Gene: vgl1 / 2539425
• PomBaseID: SPCC550.14
• Length: 1291
• Species: Schizosaccharomyces pombe
• Alignment Length: 560
• Identity: 123/560 - (21%)
• Similarity: 201/560 - (35%)
• Gaps: 131/560 - (23%)

  Fly    44 STTSV-GSGA------PSETQSEISSVDSDWSDIRAIAMKLGVQNPDDLHTER--FKVDRQKLEQ 99
            |.||| ||.:      |....|..||..|..|.::          ..|..||.  ...|.|....
pombe   122 SNTSVAGSDSVSRDKIPFSASSRASSTKSTLSSVK----------ETDFVTETLILSPDNQAPRM 176

  Fly   100 LIKAESSIEGMNGAEYFFHDIMNTTDTYVSWPCRLKIGAKSK-KDPHVRIVGKVDQVQRAKERIL 163
                 |.:...|........:|:.|.|      |:.:...|| |:....|.||...|:.|:.:||
pombe   177 -----SFVGKPNSVAEIVRTVMHQTST------RINVSTASKTKNTTFLIQGKTSAVKAARRQIL 230

  Fly   164 SSLDSRGTRVIMKMDVSYTDHSYIIGRGGNNIKRIMDDTHTHIHFPDSNRS---------NPTEK 219
            ..:..|.|:. |...|...  ..|||..|.|:|.|||.|.|.|..|..|.:         .|.::
pombe   231 KLIGRRETKT-MPCPVFVV--GAIIGTNGQNLKSIMDRTSTRIQIPKRNNTANESSDDAKKPEKE 292

  Fly   220 SNQ----------------VSLCGSLEGVERAR-------------ALVRLSTPLLISFEM--PV 253
            .|.                :::.|..||||.|:             ..||:|.   ||.|:  .:
pombe   293 ENSAASTLDDLEPQYEMTTITIEGDFEGVELAQKDIEAIINERTSNTTVRISH---ISTELYSLL 354

  Fly   254 MGPNKPQPDHETPYIKMIE--TKFNVQVIFS-TRPKLHTSLVLVKGSEKESAQVRDATQLLINFA 315
            .||:...       ||.:|  ....||:.|: ..|....:.:::.|   |.:.||:....|...|
pombe   355 RGPDGKN-------IKELEEGRDLKVQIPFAYLDPSAPVNPIVLSG---EKSAVRECALYLQGQA 409

  Fly   316 CESIASQILVNVQMEISPQHHEIVKGKNNVNLLSIMERTQTKIIFPDLS-DMNVKPLKKSQVTIS 379
            .|.:.:.|  ...:.|..:.|..:.|:..|.:..|:.::...:|.|.:: |.:|..::...:.||
pombe   410 EELLRTTI--PTMLPIPRRQHRFINGEKGVGIQDILRKSGCSVILPPINGDSDVVSVRGPALNIS 472

  Fly   380 GRID-DVYLARQQLLGNLPVALIFDFPDNHNDASEIMS-----------LNTKYGVYITLRQK-- 430
            ..|. .:..|...::..:.:...:....|..|.:.|::           |..:..|...|.::
pombe   473 EGIRLTLERANSTIVDAVNITTAYASSKNPFDIASIVARLFLRSRKLIPLEEECAVQYHLPKREE 537

  Fly   431 -QRQSTLAIVVKGVEKFIDKIYEARQEILRLATPF---------VKPEIPDYYFMPKDKDLNLAY 485
             |..|...::::...|..:.:.|.|.::|.|...|         :.|.:..|....|.|:|....
pombe   538 LQSNSNKTVIIEISGKSQEAVREGRAKLLALVNQFPESKFYKVTIDPLLQRYVIGSKGKNLQKLR 602

  Fly   486 RTQLTALLAG------------YV--DSPKTPSLLPPSLA 511
            ......||.|            |:  |..|:|..:...||
pombe   603 NEHQVELLVGEYGEEDPDVIVCYIGADDGKSPDQIQKELA 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BicC	NP_476865.1	vigilin_like_KH	174..240	CDD:239087	24/103 (23%)
		vigilin_like_KH	327..393	CDD:239087	13/67 (19%)
		SAM_BICC1	805..868	CDD:188919
		SAM	807..867	CDD:197735
vgl1	NP_588106.2	KH-I	238..329	CDD:238053	25/93 (27%)
		KH-I	345..406	CDD:294072	16/73 (22%)
		vigilin_like_KH	421..473	CDD:239087	10/51 (20%)
		vigilin_like_KH	578..>623	CDD:239087	8/44 (18%)
		vigilin_like_KH	660..727	CDD:239087
		KH	741..802	CDD:197652
		vigilin_like_KH	810..884	CDD:239087
		KH_1	896..957	CDD:278442
		vigilin_like_KH	969..1041	CDD:239087
		KH-I	1052..1115	CDD:238053
		vigilin_like_KH	1223..1280	CDD:239087

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.860