Protein Alignment BicC and bcc-1

DIOPT Version :9

• Sequence 1: NP_476865.1
• Gene: BicC / 34946
• FlyBaseID: FBgn0000182
• Length: 905
• Species: Drosophila melanogaster
• Sequence 2: NP_502067.2
• Gene: bcc-1 / 178008
• WormBaseID: WBGene00000246
• Length: 644
• Species: Caenorhabditis elegans
• Alignment Length: 843
• Identity: 199/843 - (23%)
• Similarity: 318/843 - (37%)
• Gaps: 279/843 - (33%)

  Fly    79 VQNPDDLHTERFKVDRQKLEQLI--KAESSIEGMNGAEYFFHDIMNTTDTYVSWPCRLKIGAKSK 141
            :|.||....::.:|||:|||.:|  :.:::...:..||.||.::|:.::..|.||.:||||||:|
 Worm     8 IQLPDGRFEQKIQVDRRKLESMITGRIDNTSHQLPTAESFFANVMSYSNAEVIWPSQLKIGAKTK 72

  Fly   142 KDPHVRIVGKVDQVQRAKERILSSLDSRGTRVIMKMDVSYTDHSYIIGRGGNNIKRIMDDTHTHI 206
            |||:|:::|.::|::.|:..:|:||..:..||.:||::.::.||:|||:||..|:::|..|..||
 Worm    73 KDPYVKVIGSIEQIESARTLVLNSLQIKKERVSLKMELHHSLHSHIIGKGGRGIQKVMKMTSCHI 137

  Fly   207 HFPDSNRSNPTEKSNQVSLCGSLEGVERARALVRLSTPLLISFEMPVMGPNKP-------QPDHE 264
            ||||||:.:.:.||:|||:.|:...|..|...:|...||.:..::|...|.:|       |.|.:
 Worm   138 HFPDSNKYSDSNKSDQVSISGTPVNVFEALKHLRSMCPLTVYMKLPWYNPGQPDLRPLMSQMDLD 202

  Fly   265 TPY--------IKMIETKFNVQVIFSTRPKLHTSLVLVKGSEKESAQVRDATQLLINFACESIAS 321
            ...        |||..:: :..|:|:.|..||..|:               |:..:|.:.:.:|.
 Worm   203 VSVEQNIYSLAIKMTGSQ-DASVLFAIRLVLHHFLL---------------TEEYLNISTQVLAR 251

  Fly   322 QILVNVQMEISPQHHEIVK---GKNNVNLLSIMERTQTKIIFPDLSDMNVKPLKKSQVTISGRID 383
            :.| |.|:|...:|.|.::   .||||.:.:..|.....|:.|....:||:.|
 Worm   252 EEL-NYQLENVEEHRERLREVCNKNNVTIQTFPETQSISIVGPPSGVLNVRKL------------ 303

  Fly   384 DVYLARQQLLGNLPVALIFD--FPDNHNDASEIMSLNTKYGVYITLRQKQRQSTLAIVVKGVEKF 446
                    |:|...|.:.||  ..|.|   ..:..|..:.|:.:|.::| ....:.|.:|..|..
 Worm   304 --------LIGLSSVTVQFDCNMMDIH---YPVQQLEQERGIQVTCKRK-NGDIMTITMKSTESK 356

  Fly   447 IDKIYEARQEILRLATPFVKPEIPDYYFMPKDKDLNLAYRTQLTALLAGYVDSPKTPSLLPPSLA 511
            :.::.::|:  |.||.|      |..|..|.|.|                   |......||||
 Worm   357 LAEVLQSRE--LLLALP------PTTYSSPDDYD-------------------PNPVMSRPPSL- 393

  Fly   512 GQLTPYANNNHLLLNANGLATPTGVCAPTQKYMQLHNSFQQAQNRSMVAGGQSNNGNYLQVPGAV 576
                                      .|.|..|               |.|             |
 Worm   394 --------------------------TPLQTEM---------------ASG-------------V 404

  Fly   577 APPLKPPTVSPRNSCSQNTSGYQSFSSSTTSLEQSYPPYAQLPGTVSSTSSSTAGSQNRAHYSPD 641
            ...|.||..||:                                                  |||
 Worm   405 RVFLTPPIESPK--------------------------------------------------SPD 419

  Fly   642 STYGSEGGGVGGGGGGGARLGRRLSDGVLLGLSNSNGGGGNSGGAHLLPGSAESYRSLHYDLGGN 706
            .                       .|..|              .|.:|.|:.:.  |.:.|:...
 Worm   420 P-----------------------EDSPL--------------AASILKGAKDI--SKNSDIWKK 445

  Fly   707 KHSGHRAFDFDMKRALGYKAMERTPVAGELRTPTTAWMGMGLSSTSPA----------------- 754
            |....|. :..:|..   :|:....|....|.||..|.|.|.||:.||
 Worm   446 KSKADRG-EMLIKAT---QAIFDDSVLSSPRYPTDLWSGYGFSSSLPADLLKGMMDLSTNEPSTN 506

  Fly   755 -PAPLENGENG-----------------AAGGGASSGWRLPPGLGSPYGLSATTGLLDAT--PVN 799
             |..:.:.:.|                 :...|.|..:..||    ....||:|.:.|:.  |.|
 Worm   507 GPPMMNHSQRGLCSVREEDEELSDFSASSTNYGMSRIFEQPP----RNVFSASTSVFDSNSLPYN 567

  Fly   800 RRMQLAKHKDIQTLLTSLGLEHYIKIFVLNEIDLEVFTTLTEENLMELGIAAFGARKKLLTAI 862
            .:..:....|...:|..||...|:......|||:..|..|.|:||.::|::..|||||:..||
 Worm   568 LQWDINYFTDPSMVLAQLGCSEYMTQLRDQEIDMHAFLLLDEQNLKDIGVSTIGARKKIHHAI 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BicC	NP_476865.1	vigilin_like_KH	174..240	CDD:239087	28/65 (43%)
		vigilin_like_KH	327..393	CDD:239087	14/68 (21%)
		SAM_BICC1	805..868	CDD:188919	21/58 (36%)
		SAM	807..867	CDD:197735	21/56 (38%)
bcc-1	NP_502067.2	vigilin_like_KH	105..171	CDD:239087	28/65 (43%)
		SAM	571..636	CDD:197735	21/60 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159378
Domainoid	1	1.000	80	1.000	Domainoid score	I5559
eggNOG	1	0.900	-	-		E1_KOG2208
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	221	1.000	Inparanoid score	I2280
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004093
OrthoInspector	1	1.000	-	-		oto19915
orthoMCL	1	0.900	-	-		OOG6_108156
Panther	1	1.100	-	-	LDO	PTHR10627
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3867
SonicParanoid	1	1.000	-	-		X4464
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.780