DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment BicC and tofu-7

DIOPT Version :9

Sequence 1:	NP_476865.1	Gene:	BicC / 34946	FlyBaseID:	FBgn0000182	Length:	905	Species:	Drosophila melanogaster
Sequence 2:	NP_498547.1	Gene:	tofu-7 / 175988	WormBaseID:	WBGene00022737	Length:	279	Species:	Caenorhabditis elegans

Alignment Length:	213	Identity:	42/213 - (19%)
Similarity:	76/213 - (35%)	Gaps:	66/213 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 ADVAKPPMVGLEVEAGSIGSL-----SSLHALPSTTSVGSGAPSETQSEIS------SVDSDWSD 69
            ||.:|...:  .:.|.::|::     .:|..|...|.......|.|..|:.      |.|::|::
Worm    51 ADASKDYFI--RIPAFAVGAVVGKRGMTLRRLMYETQTECVLRSYTPEELDVASNEVSADAEWTE 113

  Fly    70 IRAIAMKLGVQNPDDLHTERFKVDRQKLEQLIKAESSIEGMNGAEYFFHDIMNTTDTYVSWPCRL 134
                    ..|| :|...|.....|:|:..|                   ::..||
Worm   114 --------QFQN-EDWFGEESTDTRRKITYL-------------------LVRATD--------- 141

  Fly   135 KIGAKSKKDPHVRIVGKVDQVQRAKERILSSLDSRGTRVIMKMDVSYTDHSYIIGRGGNNIKRIM 199
               .:..|...:||...:|.||:..:.....::   |:::          .|::||||.:||.:.
Worm   142 ---EQCVKLVRLRIAEIIDNVQKPWKTAEFEVE---TQMV----------GYLVGRGGRHIKTLR 190

  Fly   200 DDTHTHIHFPDSNRSNPT 217
            |....:|...|....:||
Worm   191 DKFSVNIQISDPIPDDPT 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BicC	NP_476865.1	vigilin_like_KH	174..240	CDD:239087	12/44 (27%)
		vigilin_like_KH	327..393	CDD:239087
		SAM_BICC1	805..868	CDD:188919
		SAM	807..867	CDD:197735
tofu-7	NP_498547.1	KH	59..>110	CDD:197652	10/52 (19%)
tofu-7	NP_498547.1	KH_1	165..>216	CDD:278442	13/57 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900