Protein Alignment BicC and BicC

DIOPT Version :10

• Sequence 1: NP_476865.1
• Gene: BicC / 34946
• FlyBaseID: FBgn0000182
• Length: 905
• Species: Drosophila melanogaster
• Sequence 2: XP_061513633.1
• Gene: BicC / 1280232
• VectorBaseID: AGAMI1_007798
• Length: 935
• Species: Anopheles gambiae
• Alignment Length: 1014
• Identity: 446/1014 - (43%)
• Similarity: 588/1014 - (57%)
• Gaps: 193/1014 - (19%)

  Fly     1 MLSCASFNKLMYPSAADVAKPPMVGLEVEAGSIGSLSSLHALPSTTSVGSGAPSETQSEISSVDS 65
            |.||:||||.::                                   :..|.||||.||||||:|
Mosquito     2 MASCSSFNKHIF-----------------------------------LNGGPPSETTSEISSVES 31

  Fly    66 DWSDIRAIAMKLGVQNPDDLHTERFKVDRQKLEQLIKAESSIEGMNGAEYFFHDIMNTTDTYVSW 130
            ||.|:|.||.:|||.||||||.|||||||||||.:||.|:..||||.||.||.:||..|.|||||
Mosquito    32 DWGDLRLIAAQLGVANPDDLHVERFKVDRQKLEDMIKVETYSEGMNSAEEFFTNIMKETTTYVSW 96

  Fly   131 PCRLKIGAKSKKDPHVRIVGKVDQVQRAKERILSSLDSRGTRVIMKMDVSYTDHSYIIGRGGNNI 195
            |||||||||:|||||:|||||:..|.|||:::::.|||||:||||||||||||||:|||||||||
Mosquito    97 PCRLKIGAKTKKDPHIRIVGKMADVLRAKDKVMARLDSRGSRVIMKMDVSYTDHSFIIGRGGNNI 161

  Fly   196 KRIMDDTHTHIHFPDSNRSNPTEKSNQVSLCGSLEGVERARALVRLSTPLLISFEMPVMGPNKPQ 260
            |:||::|.|||||||||||||||||||||:|||:|||||||:|||.|||||||||:|::.|.|..
Mosquito   162 KKIMEETATHIHFPDSNRSNPTEKSNQVSMCGSIEGVERARSLVRNSTPLLISFELPILAPGKTP 226

  Fly   261 PDHETPYIKMIETKFNVQVIFSTRPKLHTSLVLVKGSEKESAQVRDATQLLINFACESIASQILV 325
            ||::|||:|.||.::.||||||||||||:|||||||||||...|::||:.|::..||::||||.|
Mosquito   227 PDNDTPYVKEIEAEYGVQVIFSTRPKLHSSLVLVKGSEKEERMVKEATRRLMDLMCENMASQIPV 291

  Fly   326 NVQMEISPQHHEIVKGKNNVNLLSIMERTQTKIIFPDLSDMNVKPLKKSQVTISGRIDDVYLARQ 390
            ::|:|||.|||.||.|:::.||..||.||.|:|:|||.:|:|:||:|:|||||:|.|:.||||||
Mosquito   292 HMQLEISTQHHPIVLGRSSSNLREIMNRTGTQIMFPDANDVNIKPIKRSQVTITGSINGVYLARQ 356

  Fly   391 QLLGNLPVALIFDFPDNHNDASEIMSLNTKYGVYITLRQKQRQSTLAIVVKGVEKFIDKIYEARQ 455
            ||:|:||:|||||:|:|..|:.||..|...:.|:|::|||.|||||.||:||:||||..|||||.
Mosquito   357 QLIGSLPIALIFDYPENTVDSDEITKLMLTHDVFISVRQKSRQSTLCIVIKGIEKFIANIYEARH 421

  Fly   456 EILRLATPFVKPEIPDYYFMPKDKDLNLAYRTQLTALLAGYVDSPKTP----------------- 503
            ::|:.....|..|||..||.|.:.....:  ..::|||||.|..|.:|
Mosquito   422 QLLKGGGARVVAEIPRTYFGPNEHPQQTS--QNISALLAGPVAPPFSPLSPINPLPFVGWPTPTS 484

  Fly   504 --------------SLLPPS------LAGQLTPY---------ANNNHLLL-------------- 525
                          :.||.|      :.||...:         ...:|.||
Mosquito   485 AAAAAAAVAAAAAAASLPSSDFAFSHMRGQFQNFHVHGPGKLPTGQHHQLLPLSLPPGLERTVPG 549

  Fly   526 -----NANGLATPTGVCAP--------TQKYMQ----LHNSFQQAQNRSMVA------GGQSNNG 567
                 ..|.|::|..:..|        :..|:|    .|::.||.|......      ..|.:||
Mosquito   550 GSSAGKMNHLSSPHLLSVPGHGVGGGGSASYLQNQQHQHHAQQQQQQHHHTTHSHHQRNQQHSNG 614

  Fly   568 NYLQVPGAVAPPLKPPTVSPRNSCSQ-NTSGYQSFSSSTTSLEQSYPPYAQLPGTVSSTSSSTAG 631
            |.     :.:..|   |||..:|.:. ::|||||.:.|:.||:|.:...:...|:||..||::..
Mosquito   615 NC-----STSTSL---TVSQNSSHNDIHSSGYQSLNCSSNSLDQQFQSNSSASGSVSQVSSNSLL 671

  Fly   632 SQNRAHYSPDSTYGSEGGGVGGGGGGGARLGR-RLSDGVLLGLSNSNGGGGNSGGAHLLPGSAES 695
            :.:..|.||             |..|.:.|.| |||      :.........|......|.:.|.
Mosquito   672 NSSPDHQSP-------------GAAGTSGLNRCRLS------VCTPESPHYQSELEQRTPLAFEQ 717

  Fly   696 YRSLHYDLGGNKHSGHRAFDFDMKRALGYKAMERTPVAGELRTPTTAWMGMGLSSTSPAPAPLE- 759
            ..||         :....|:.|.:...|||||..:|..||:||||.:|.|:|||.:|  |||||
Mosquito   718 KSSL---------ADTFLFNLDPRVVAGYKAMHMSPQQGEIRTPTLSWQGLGLSQSS--PAPLEA 771

  Fly   760 -----------NGENGAAGGGASSGWRLPPGLGSPYGL-----SATTGLLDATPVNRRMQLAKHK 808
                       :...|...||..||........|..|.     :.||.:::.||.::|.|::::.
Mosquito   772 CDLSWANTSSSSSTGGGRDGGGGSGCANTSTSSSSSGAADSRHNMTTTMIEVTPRHQREQMSQYN 836

  Fly   809 DIQTLLTSLGLEHYIKIFVLNEIDLEVFTTLTEENLMELGIAAFGARKKLLTAIHTLLANEA--- 870
            |:.|:||.||||||||.|:..|||:.||.|||:::|:.|.|...|||:::|.|||.|...:.
Mosquito   837 DVTTILTGLGLEHYIKNFINGEIDMTVFQTLTDQDLLNLDIKPLGARRRILMAIHDLSVRQGGGL 901

  Fly   871 ------ACSTMPSSSSSQNSSSPRFSGSAAPGAERRPSN 903
                  :.|.:|||.|       |||||||||||||.|:
Mosquito   902 FGSSALSPSALPSSLS-------RFSGSAAPGAERRSSS 933

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BicC	NP_476865.1	KH-I_BICC1_rpt1	85..166	CDD:411848	55/80 (69%)
		KH-I_BICC1_rpt2	171..240	CDD:411849	59/68 (87%)
		KH-I_BICC1_rpt3	325..393	CDD:411850	41/67 (61%)
		SAM_BICC1	805..868	CDD:188919	32/62 (52%)
BicC	XP_061513633.1	None