DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment beat-Ic and F11R

DIOPT Version :9

Sequence 1:	NP_001285970.1	Gene:	beat-Ic / 34945	FlyBaseID:	FBgn0028644	Length:	534	Species:	Drosophila melanogaster
Sequence 2:	NP_001369656.1	Gene:	F11R / 50848	HGNCID:	14685	Length:	327	Species:	Homo sapiens

Alignment Length:	160	Identity:	37/160 - (23%)
Similarity:	63/160 - (39%)	Gaps:	39/160 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 TEKDVGSHG---SQSGRSCICWISVVLLLILVPDFIEALKDVSVMIPQAVKRGSNALFTCNYDME 83
            |.:|.|::.   |:.|.:....:.|.|::::.|      ...:|.||.:...|:.|:.||: :.:
Human   100 TREDTGTYTCMVSEEGGNSYGEVKVKLIVLVPP------SKPTVNIPSSATIGNRAVLTCS-EQD 157

  Fly    84 NDTLYSVKWYKGKREFYRYTPKENPAMKVFAMTSGLNVERNLSNQSHVV------LQSVPLNIS- 141
            ........|:|..                ..|.:.....|..||.|:|:      |...||:.|
Human   158 GSPPSEYTWFKDG----------------IVMPTNPKSTRAFSNSSYVLNPTTGELVFDPLSASD 206

  Fly   142 -GKFTCEISVEAPTFQTAMVSG--EMEVVE 168
             |:::||   ....:.|.|.|.  .||.||
Human   207 TGEYSCE---ARNGYGTPMTSNAVRMEAVE 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
beat-Ic	NP_001285970.1	Ig	189..>246	CDD:299845
F11R	NP_001369656.1	IgV_1_JAM1-like	30..129	CDD:409538	7/28 (25%)
		Ig strand B	46..50	CDD:409538
		Ig strand C	59..63	CDD:409538
		Ig strand E	92..96	CDD:409538
		Ig strand F	106..111	CDD:409538	0/4 (0%)
		Ig strand G	121..124	CDD:409538	0/2 (0%)
		IgI_2_JAM1	135..231	CDD:409542	26/115 (23%)
		Ig strand B	149..153	CDD:409542	1/3 (33%)
		Ig strand C	163..167	CDD:409542	0/3 (0%)
		Ig strand E	195..199	CDD:409542	1/3 (33%)
		Ig strand F	209..214	CDD:409542	2/7 (29%)
		Ig strand G	224..227	CDD:409542	1/2 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910