DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment beat-Ic and beat-VI

DIOPT Version :9

Sequence 1:	NP_001285970.1	Gene:	beat-Ic / 34945	FlyBaseID:	FBgn0028644	Length:	534	Species:	Drosophila melanogaster
Sequence 2:	NP_001263035.1	Gene:	beat-VI / 43377	FlyBaseID:	FBgn0039584	Length:	332	Species:	Drosophila melanogaster

Alignment Length:	382	Identity:	101/382 - (26%)
Similarity:	161/382 - (42%)	Gaps:	85/382 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 ANRWRTEKDVGSHGSQSGRSC-------------ICWISVVLLLILVPDFIEALKDVSVMIPQAV 68
            :.|.|:..:.|..|.:...:|             :.||.:..||:..    ..|||:.:.:|:||
  Fly     3 SQRIRSRPEEGRKGRRMSSACRPGALHTAFNMLALSWIIISELLLSA----HCLKDLKIFVPEAV 63

  Fly    69 KRGSNALFTCNYDMENDTLYSVKWYKGKREFYRYTPKENPAMKVFAMTSGLNVERNLSNQSHVVL 133
            ..|:.|..:|.||:|...||:|:||.|:.|||||.|:|.....|||: :|:||:...|:.:.|.|
  Fly    64 LMGNAATLSCQYDLEQAALYAVRWYFGQEEFYRYVPREAKPTFVFAV-AGINVDLANSDATSVTL 127

  Fly   134 QSVPLNISGKFTCEISVEAPTFQTAMVSGEMEVVELPEEHTVVTGIQARYRIGDLVDGNCSIKYS 198
            :.|...:||.:.||:|.:||.|.|.:.|..|:|:|||::..|:...:....:.|.....|::..|
  Fly   128 KGVTRELSGSYQCEVSEDAPLFHTEIRSAHMQVIELPKDDPVMQVDKKVIGVNDNFKAVCTVGPS 192

  Fly   199 KPAANLTWTINGIVVPPHHIKTYQTEKRENSTLE-SVTSAIHFMVTNQHFLKG--------QMRL 254
            .|.||:||:|||     :.|:....::....|.| |.|.:...:..|...|:|        .:.|
  Fly   193 YPPANITWSING-----NQIRRTPLQRISQDTYEGSTTYSSLDIYPNSQALQGFFETKYQHSVNL 252

  Fly   255 KCTANIFDIFKEEMESVIEEDRPRIMASGRSYDINNYPLE---EHTNGERGGFEDHNESYLTYYS 316
            :|...|..::    ..|:.:......|...:...|...||   .:.||:
  Fly   253 QCVVTIRHMY----HKVVAQRIGLNAAPPTTISPNLLGLEGSKRYANGD---------------- 297

  Fly   317 ADNTASGASTAAHEIFWQFWPSQLTKLPINRQLAGAWH---WLCGGGGAAALLLFFL 370
                                       |.|..|.||..   ..||..||.:|.:|.|
  Fly   298 ---------------------------PDNSALTGASQRCCICCGAFGAVSLAIFTL 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
beat-Ic	NP_001285970.1	Ig	189..>246	CDD:299845	16/57 (28%)
beat-VI	NP_001263035.1	Ig	66..142	CDD:416386	32/76 (42%)
		Ig strand B	67..76	CDD:409353	2/8 (25%)
		CDR1	76..83	CDD:409353	2/6 (33%)
		Ig strand C	83..91	CDD:409353	4/7 (57%)
		FR2	84..91	CDD:409353	3/6 (50%)
		CDR2	94..108	CDD:409353	6/13 (46%)
		Ig strand C'	94..99	CDD:409353	4/4 (100%)
		Ig strand C'	102..104	CDD:409353	0/1 (0%)
		FR3	109..143	CDD:409353	12/34 (35%)
		Ig strand D	117..121	CDD:409353	0/3 (0%)
		Ig strand E	123..127	CDD:409353	1/3 (33%)
		Ig strand F	136..144	CDD:409353	3/7 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000798
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR21261
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.010