DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment beat-Ic and beat-Ia

DIOPT Version :9

Sequence 1:	NP_001285970.1	Gene:	beat-Ic / 34945	FlyBaseID:	FBgn0028644	Length:	534	Species:	Drosophila melanogaster
Sequence 2:	NP_001285975.1	Gene:	beat-Ia / 34947	FlyBaseID:	FBgn0013433	Length:	437	Species:	Drosophila melanogaster

Alignment Length:	491	Identity:	155/491 - (31%)
Similarity:	242/491 - (49%)	Gaps:	95/491 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 LLLILVPDFIEALKDVSVMIPQAVKRGSNALFTCNYDMENDTLYSVKWYKGKREFYRYTPKENPA 109
            :||.|..:...||:||.|.:|.||:|...|:..|.||:|:|:|||||||||:||||||||||.|.
  Fly    15 ILLALTLEMTAALRDVRVRVPHAVRRSEKAILKCFYDIEDDSLYSVKWYKGRREFYRYTPKETPP 79

  Fly   110 MKVFAMTSGLNVERNLSNQSHVVLQSVPLNISGKFTCEISVEAPTFQTAMVSGEMEVVELPEEHT 174
            ||||.. .|:.|.|..||:|.|||.:|.:..|||::||:|.:||:|.|.:.:.|:||:|.|....
  Fly    80 MKVFHF-PGVKVRRVSSNESQVVLDAVTMATSGKYSCEVSADAPSFHTLIAAAELEVIETPHNAP 143

  Fly   175 VVTGIQARYRIGDLVDGNCSIKYSKPAANLTWTINGIVVPPHHIKTYQTEKRENSTLESVTSAIH 239
            .:|||:.|||:||::.|||:.::|:||||||||:|...|.|..::.::..:...:.:|:....||
  Fly   144 FITGIRPRYRVGDILRGNCTSRHSRPAANLTWTVNNEEVNPALVRHHKILRDARNDMETAVVGIH 208

  Fly   240 FMVTNQHFLKGQMRLKCTANIFDIFKEEMESVIEEDRPRIMASGRSYDINNYPLEEHTNGERGGF 304
            |:||:|||..|:::|:|:|.:.|::.:..|.:|.|.           |:  :|  :|.||..|..
  Fly   209 FVVTDQHFDNGKLKLRCSAQLHDVYWKTTEKIILET-----------DL--FP--KHGNGANGNH 258

  Fly   305 EDHNESYLTYYSAD----NTASGASTAAHEIFWQFWPSQLTKLPINRQLAGAWHWLCGGGGAAAL 365
            .:.::.|..|...:    |..:...|...|.|:..:      :|...:..|....| |.||||
  Fly   259 VNPDDFYDQYALHEDHLHNKKNSYLTQLQEFFFYHF------VPSGEEDDGTEGGL-GDGGAA-- 314

  Fly   366 LLFFLLQQGPLGHQIINCQYTKPATGKVQQQQRNSGSSSNIEVTASKAATSSASSVKCFYNCQMA 430
                                           .|.:||||      |:.:.||:.|........||
  Fly   315 -------------------------------WRGAGSSS------SRLSPSSSQSCWMVGGSLMA 342

  Fly   431 MAMPTRSRDDDDDGGDAYIGSTSANATATATATADADAADVAAAGGVASCSIKRLSATLVGGVNA 495
            :...|.:|.        .:....|..|.|..||.:..          ..|:.:|..|      :.
  Fly   343 VLSWTLARQ--------LVSPLQAMMTKTGGATCNMS----------GRCASRRTRA------HG 383

  Fly   496 VRGVASGPDQRLLMTRRRERRQKKSQAMDAMMQSRW 531
            :|..|:...|     ::|:.:|:..::...:.:|.|
  Fly   384 MRVSATKQKQ-----KQRQMQQEHRKSCLRVSKSSW 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
beat-Ic	NP_001285970.1	Ig	189..>246	CDD:299845	21/56 (38%)
beat-Ia	NP_001285975.1	Ig	32..118	CDD:299845	50/86 (58%)
beat-Ia	NP_001285975.1	Ig	161..240	CDD:299845	29/78 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469213
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2A48N
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	42	1.000	Inparanoid score	I5491
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D78626at33392
OrthoFinder	1	1.000	-	-		FOG0000798
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR21261
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.900