DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10839 and NUD1

DIOPT Version :9

Sequence 1:	NP_001246039.1	Gene:	CG10839 / 34944	FlyBaseID:	FBgn0028858	Length:	182	Species:	Drosophila melanogaster
Sequence 2:	NP_015018.3	Gene:	NUD1 / 854555	SGDID:	S000005900	Length:	851	Species:	Saccharomyces cerevisiae

Alignment Length:	174	Identity:	47/174 - (27%)
Similarity:	78/174 - (44%)	Gaps:	33/174 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 GLQFQYPPI---EKMDPILNSLTECQKLSLSSNMIE------KIT----GISGMKNLKVLSLARN 80
            |:|...|.:   ...|..:|:|.     .:.||:::      |||    .::|..:|:.|.|:.|
Yeast   494 GMQRLLPNVLVLNLSDNEMNTLE-----GIPSNVVQLFCSNNKITSAHCSLAGFHDLECLDLSYN 553

  Fly    81 NLKTLNGIEPLADTLEELWVSYNNIEKTKPLES--MKALRVFYISFNMIKDWTEFMRMGVPPNLS 143
            .|.|......|...|:|:.:|||:|:..:.:.|  ||.|.:.....|.|.|:.:.:       |:
Yeast   554 LLNTSLKFLSLCHHLQEVNLSYNSIQSLEGIGSSRMKKLNLSNNEINGIIDFEQLI-------LT 611

  Fly   144 EITFVGNPLN-ENMDQSAFTAEAVRR---LPNMK--KLDGEPVI 181
            ..:.||..|. |.:|.|......||.   ||.:|  .|:|.|::
Yeast   612 NNSVVGGWLTVEVLDLSNNNIIGVRNINCLPRLKVLNLNGNPLV 655

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10839	NP_001246039.1	LRR_RI	<37..129	CDD:238064	28/106 (26%)
		LRR_4	48..90	CDD:289563	12/51 (24%)
		leucine-rich repeat	50..71	CDD:275380	6/30 (20%)
		LRR_8	51..105	CDD:290566	18/63 (29%)
		leucine-rich repeat	72..94	CDD:275380	7/21 (33%)
		leucine-rich repeat	95..116	CDD:275380	8/22 (36%)
		leucine-rich repeat	117..141	CDD:275380	4/23 (17%)
		leucine-rich repeat	142..171	CDD:275380	10/32 (31%)
NUD1	NP_015018.3	LRR	<440..662	CDD:227223	47/174 (27%)
		leucine-rich repeat	522..544	CDD:275380	4/21 (19%)
		leucine-rich repeat	545..567	CDD:275380	7/21 (33%)
		PPP1R42	557..784	CDD:411060	30/106 (28%)
		leucine-rich repeat	568..588	CDD:275380	7/19 (37%)
		leucine-rich repeat	589..621	CDD:275380	9/38 (24%)
		leucine-rich repeat	622..643	CDD:275380	6/20 (30%)
		leucine-rich repeat	699..738	CDD:275380
		leucine-rich repeat	739..768	CDD:275380
		leucine-rich repeat	794..806	CDD:275378
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900