DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10839 and SDS22

DIOPT Version :9

Sequence 1:	NP_001246039.1	Gene:	CG10839 / 34944	FlyBaseID:	FBgn0028858	Length:	182	Species:	Drosophila melanogaster
Sequence 2:	NP_012728.1	Gene:	SDS22 / 853641	SGDID:	S000001676	Length:	338	Species:	Saccharomyces cerevisiae

Alignment Length:	175	Identity:	44/175 - (25%)
Similarity:	88/175 - (50%)	Gaps:	10/175 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LKDALAKWEDRNKQPAATATEIGLQFQYPPIEKMDP-ILNSLTECQKLSLSSNMIEKITGISGMK 70
            ::::::|.|:.:...:....|:|..    .:..::| ....|:..:::.|..|.|.::..:..:|
Yeast   143 VQNSISKIENLSTLKSLKNLELGGN----KVHSIEPDSFEGLSNLEEIWLGKNSIPRLINLHPLK 203

  Fly    71 NLKVLSLARNNLKTLNGIEPLADTLEELWVSYNNIEKTKPLESMKALRVFYISFNMIKDWTEFMR 135
            |||:||:..|.||.:..:|.|.: ||||::|:|.|.|.:.||....|....::.|.|   |....
Yeast   204 NLKILSIQSNKLKKIENLEELTN-LEELYLSHNFITKIEGLEKNLKLTTLDVTSNKI---TSLEN 264

  Fly   136 MGVPPNLSEITFVGNPLNENMDQSAFTAEAVRRLPNMKKLDGEPV 180
            :....||::|....|.::::.:.......|:.||..: .|:|.|:
Yeast   265 LNHLSNLTDIWASFNKIDQSFESLGENLSALSRLETI-YLEGNPI 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10839	NP_001246039.1	LRR_RI	<37..129	CDD:238064	29/92 (32%)
		LRR_4	48..90	CDD:289563	12/41 (29%)
		leucine-rich repeat	50..71	CDD:275380	3/20 (15%)
		LRR_8	51..105	CDD:290566	20/53 (38%)
		leucine-rich repeat	72..94	CDD:275380	9/21 (43%)
		leucine-rich repeat	95..116	CDD:275380	10/20 (50%)
		leucine-rich repeat	117..141	CDD:275380	4/23 (17%)
		leucine-rich repeat	142..171	CDD:275380	6/28 (21%)
SDS22	NP_012728.1	inl_like_NEAT_1	<42..>174	CDD:411101	4/34 (12%)
		leucine-rich repeat	44..67	CDD:275380
		leucine-rich repeat	68..91	CDD:275380
		leucine-rich repeat	92..114	CDD:275380
		PPP1R42	112..332	CDD:411060	44/175 (25%)
		leucine-rich repeat	115..136	CDD:275380
		leucine-rich repeat	137..158	CDD:275380	2/14 (14%)
		leucine-rich repeat	159..182	CDD:275380	4/26 (15%)
		leucine-rich repeat	183..204	CDD:275380	3/20 (15%)
		leucine-rich repeat	205..248	CDD:275380	19/43 (44%)
		leucine-rich repeat	249..270	CDD:275380	4/23 (17%)
		leucine-rich repeat	271..294	CDD:275380	3/22 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900