Protein Alignment CG10839 and DNAL1

DIOPT Version :9

• Sequence 1: NP_001246039.1
• Gene: CG10839 / 34944
• FlyBaseID: FBgn0028858
• Length: 182
• Species: Drosophila melanogaster
• Sequence 2: NP_113615.2
• Gene: DNAL1 / 83544
• HGNCID: 23247
• Length: 190
• Species: Homo sapiens
• Alignment Length: 183
• Identity: 97/183 - (53%)
• Similarity: 135/183 - (73%)
• Gaps: 1/183 - (0%)

  Fly     1 MSKPTTLKDALAKWEDRNKQPAATATEIGLQFQYPPIEKMDPILNSLTECQKLSLSSNMIEKITG 65
            |:|.||:|:|||:||::..|..:.|.||.|..|.|||||||..|:.|..|:|||||:|.||||..
Human     1 MAKATTIKEALARWEEKTGQRPSEAKEIKLYAQIPPIEKMDASLSMLANCEKLSLSTNCIEKIAN 65

  Fly    66 ISGMKNLKVLSLARNNLKTLNGIEPLADTLEELWVSYNNIEKTKPLESMKALRVFYISFNMIKDW 130
            ::|:|||::|||.|||:|.|||:|.:.|||||||:|||.|||.|.:..||.|::.|:|.|::|||
Human    66 LNGLKNLRILSLGRNNIKNLNGLEAVGDTLEELWISYNFIEKLKGIHIMKKLKILYMSNNLVKDW 130

  Fly   131 TEFMRMGVPPNLSEITFVGNPLNE-NMDQSAFTAEAVRRLPNMKKLDGEPVIR 182
            .||:::...|.|.::.||||||.| :..::.:..||.:|:|.:|||||.|||:
Human   131 AEFVKLAELPCLEDLVFVGNPLEEKHSAENNWIEEATKRVPKLKKLDGTPVIK 183

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10839	NP_001246039.1	LRR_RI	<37..129	CDD:238064	53/91 (58%)
		LRR_4	48..90	CDD:289563	25/41 (61%)
		leucine-rich repeat	50..71	CDD:275380	12/20 (60%)
		LRR_8	51..105	CDD:290566	35/53 (66%)
		leucine-rich repeat	72..94	CDD:275380	12/21 (57%)
		leucine-rich repeat	95..116	CDD:275380	13/20 (65%)
		leucine-rich repeat	117..141	CDD:275380	9/23 (39%)
		leucine-rich repeat	142..171	CDD:275380	11/29 (38%)
DNAL1	NP_113615.2	LRR_4	49..89	CDD:289563	25/39 (64%)
		LRR 1	49..70		12/20 (60%)
		leucine-rich repeat	50..71	CDD:275378	12/20 (60%)
		LRR_8	70..127	CDD:290566	34/56 (61%)
		LRR 2	71..92		13/20 (65%)
		leucine-rich repeat	72..90	CDD:275378	11/17 (65%)
		LRR 3	94..115		13/20 (65%)
		LRR_4	95..133	CDD:289563	21/37 (57%)
		leucine-rich repeat	95..116	CDD:275382	13/20 (65%)
		LRR 4	116..137		9/20 (45%)
		leucine-rich repeat	117..140	CDD:275382	9/22 (41%)
		leucine-rich repeat	142..172	CDD:275382	11/29 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146512
Domainoid	1	1.000	102	1.000	Domainoid score	I6915
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56366
OrthoDB	1	1.010	-	-		D1395642at2759
OrthoFinder	1	1.000	-	-		FOG0006128
OrthoInspector	1	1.000	-	-		otm41035
orthoMCL	1	0.900	-	-		OOG6_103843
Panther	1	1.100	-	-	O	PTHR15454
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.720