Protein Alignment CG10839 and DNAL1

DIOPT Version :10

• Sequence 1: NP_609776.1
• Gene: CG10839 / 34944
• FlyBaseID: FBgn0028858
• Length: 182
• Species: Drosophila melanogaster
• Sequence 2: NP_113615.2
• Gene: DNAL1 / 83544
• HGNCID: 23247
• Length: 190
• Species: Homo sapiens
• Alignment Length: 183
• Identity: 97/183 - (53%)
• Similarity: 135/183 - (73%)
• Gaps: 1/183 - (0%)

  Fly     1 MSKPTTLKDALAKWEDRNKQPAATATEIGLQFQYPPIEKMDPILNSLTECQKLSLSSNMIEKITG 65
            |:|.||:|:|||:||::..|..:.|.||.|..|.|||||||..|:.|..|:|||||:|.||||..
Human     1 MAKATTIKEALARWEEKTGQRPSEAKEIKLYAQIPPIEKMDASLSMLANCEKLSLSTNCIEKIAN 65

  Fly    66 ISGMKNLKVLSLARNNLKTLNGIEPLADTLEELWVSYNNIEKTKPLESMKALRVFYISFNMIKDW 130
            ::|:|||::|||.|||:|.|||:|.:.|||||||:|||.|||.|.:..||.|::.|:|.|::|||
Human    66 LNGLKNLRILSLGRNNIKNLNGLEAVGDTLEELWISYNFIEKLKGIHIMKKLKILYMSNNLVKDW 130

  Fly   131 TEFMRMGVPPNLSEITFVGNPLNE-NMDQSAFTAEAVRRLPNMKKLDGEPVIR 182
            .||:::...|.|.::.||||||.| :..::.:..||.:|:|.:|||||.|||:
Human   131 AEFVKLAELPCLEDLVFVGNPLEEKHSAENNWIEEATKRVPKLKKLDGTPVIK 183

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10839	NP_609776.1	PPP1R42	<37..152	CDD:455733	64/114 (56%)
		leucine-rich repeat	50..71	CDD:275380	12/20 (60%)
		leucine-rich repeat	72..94	CDD:275380	12/21 (57%)
		leucine-rich repeat	95..116	CDD:275380	13/20 (65%)
		leucine-rich repeat	117..141	CDD:275380	9/23 (39%)
		leucine-rich repeat	142..171	CDD:275380	11/29 (38%)
DNAL1	NP_113615.2	PPP1R42	37..181	CDD:455733	76/143 (53%)
		LRR 1	49..70		12/20 (60%)
		leucine-rich repeat	50..71	CDD:275378	12/20 (60%)
		LRR 2	71..92		13/20 (65%)
		leucine-rich repeat	72..90	CDD:275378	11/17 (65%)
		LRR 3	94..115		13/20 (65%)
		leucine-rich repeat	95..116	CDD:275382	13/20 (65%)
		LRR 4	116..137		9/20 (45%)
		leucine-rich repeat	117..140	CDD:275382	9/22 (41%)
		leucine-rich repeat	142..172	CDD:275382	11/29 (38%)