DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10839 and lrriq1

DIOPT Version :9

Sequence 1:	NP_001246039.1	Gene:	CG10839 / 34944	FlyBaseID:	FBgn0028858	Length:	182	Species:	Drosophila melanogaster
Sequence 2:	XP_009291864.1	Gene:	lrriq1 / 565257	ZFINID:	ZDB-GENE-050419-235	Length:	1511	Species:	Danio rerio

Alignment Length:	279	Identity:	49/279 - (17%)
Similarity:	87/279 - (31%)	Gaps:	116/279 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 ALAKWEDRNKQPAATATEIGL----------QFQYPPIEKMDPILNSLT--ECQKLS------LS 56
            :|:...:.||....|....||          |.:|..:::     ||:|  :|:.||      |.
Zfish   704 SLSTLSECNKLQTLTLRRCGLTSLDGLNQCSQIRYIDVQE-----NSITHVDCEGLSSLQILLLG 763

  Fly    57 SNMIEKITGISGMKNLKVLSLARNNLKTLNGIE-------------------------------- 89
            .|.:..|.|:...:||:.|.|:.||:..::|:.
Zfish   764 RNQLMNIHGLDEAQNLQTLQLSHNNISLISGLGALKMLLHLSVDHNQLLSTRGLKEIYTLLHLDC 828

  Fly    90 -------------------------------------------------PLADTLEELW------ 99
                                                             |..|.|:..|
Zfish   829 SYNYLSHVEGLENCALLNTLDLKGNSLTELPVLQNHVLLRDLYLDDNLIPSLDDLKSYWLPLLQN 893

  Fly   100 --VSYNNIEKTKPLESMKALRVFYISFNMIKDWTEF-MRMGVPPNLSEITFVGNPLNENMDQSAF 161
              |..|:|....||..:.:|:...:|.|.:.|..:. :.:....:|.|::...|||.:..:..:.
Zfish   894 LSVVQNSITHLSPLLDLVSLKTLDVSHNCLSDLQDLCLNLQECSSLQELSLTVNPLLQENNWRSL 958

  Fly   162 TAEAVRRLPNMKKLDGEPV 180
            ..|.|   |.:.||:.|.:
Zfish   959 ILETV---PGLIKLNNEQI 974

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10839	NP_001246039.1	LRR_RI	<37..129	CDD:238064	29/188 (15%)
		LRR_4	48..90	CDD:289563	15/130 (12%)
		leucine-rich repeat	50..71	CDD:275380	7/26 (27%)
		LRR_8	51..105	CDD:290566	19/148 (13%)
		leucine-rich repeat	72..94	CDD:275380	7/102 (7%)
		leucine-rich repeat	95..116	CDD:275380	7/28 (25%)
		leucine-rich repeat	117..141	CDD:275380	4/24 (17%)
		leucine-rich repeat	142..171	CDD:275380	7/28 (25%)
lrriq1	XP_009291864.1	LRR_RI	713..952	CDD:238064	41/243 (17%)
		LRR_8	713..767	CDD:290566	14/58 (24%)
		leucine-rich repeat	714..735	CDD:275380	3/20 (15%)
		leucine-rich repeat	736..756	CDD:275380	6/24 (25%)
		LRR_8	755..811	CDD:290566	12/55 (22%)
		leucine-rich repeat	757..778	CDD:275380	4/20 (20%)
		leucine-rich repeat	779..800	CDD:275380	6/20 (30%)
		leucine-rich repeat	801..822	CDD:275380	0/20 (0%)
		leucine-rich repeat	823..844	CDD:275380	0/20 (0%)
		leucine-rich repeat	845..866	CDD:275380	0/20 (0%)
		LRR_8	867..921	CDD:290566	11/53 (21%)
		leucine-rich repeat	867..890	CDD:275380	4/22 (18%)
		leucine-rich repeat	891..912	CDD:275380	5/20 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900