DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10839 and tilB

DIOPT Version :9

Sequence 1:	NP_001246039.1	Gene:	CG10839 / 34944	FlyBaseID:	FBgn0028858	Length:	182	Species:	Drosophila melanogaster
Sequence 2:	NP_608460.1	Gene:	tilB / 33130	FlyBaseID:	FBgn0014395	Length:	395	Species:	Drosophila melanogaster

Alignment Length:	169	Identity:	41/169 - (24%)
Similarity:	75/169 - (44%)	Gaps:	28/169 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 KDALAKWEDRNKQPAATATEIGLQFQYPPIEKMDPILNSLTECQKLSLSSNMIEKITGISGMKNL 72
            ::.:.|..:.|::..:|..||.|..:  .||.::.|.|...:.:.|.|.||:|.::..:..:|.|
  Fly     6 EELVRKKSEHNERLISTLEEISLHQE--DIEVIEHIQNWCRDLKILLLQSNLIARLENLHKLKRL 68

  Fly    73 KVLSLARNNLKTLNGIEPLADTLEELWVSYNNIEKTKPLESMKALRVFYISFNMIKDWTEFMRMG 137
            :.|:                       |:.||||:.:.||..::|....::.|.|::.|....:.
  Fly    69 EYLN-----------------------VAINNIERVENLEGCESLSKLDLTLNFIRELTSVESLC 110

  Fly   138 VPPNLSEITFVGNPLNENMDQSAFTAEAVRRLPNMKKLD 176
            ...||.|:..:|||.   :|...:....|..||.:..||
  Fly   111 GNYNLRELVLIGNPC---VDYPHYRDYVVATLPQLNSLD 146

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10839	NP_001246039.1	LRR_RI	<37..129	CDD:238064	22/91 (24%)
		LRR_4	48..90	CDD:289563	8/41 (20%)
		leucine-rich repeat	50..71	CDD:275380	5/20 (25%)
		LRR_8	51..105	CDD:290566	10/53 (19%)
		leucine-rich repeat	72..94	CDD:275380	2/21 (10%)
		leucine-rich repeat	95..116	CDD:275380	7/20 (35%)
		leucine-rich repeat	117..141	CDD:275380	4/23 (17%)
		leucine-rich repeat	142..171	CDD:275380	8/28 (29%)
tilB	NP_608460.1	LRR_9	1..174	CDD:258718	41/169 (24%)
		leucine-rich repeat	23..45	CDD:275378	7/23 (30%)
		LRR_4	46..86	CDD:289563	14/62 (23%)
		leucine-rich repeat	46..67	CDD:275378	5/20 (25%)
		leucine-rich repeat	68..89	CDD:275378	9/43 (21%)
		leucine-rich repeat	90..114	CDD:275378	4/23 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810