DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10839 and Cntrl

DIOPT Version :9

Sequence 1:	NP_001246039.1	Gene:	CG10839 / 34944	FlyBaseID:	FBgn0028858	Length:	182	Species:	Drosophila melanogaster
Sequence 2:	XP_006234114.1	Gene:	Cntrl / 311886	RGDID:	1305317	Length:	2336	Species:	Rattus norvegicus

Alignment Length:	183	Identity:	45/183 - (24%)
Similarity:	91/183 - (49%)	Gaps:	21/183 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KPTTLKDALAKWEDRNKQPAATATEIGLQFQYPPIEKMDPILNSLTECQK---LSLSSNMIEKIT 64
            |..|.:|.||..:..|   .:.:.:.|.:|:|         :.:|.:|.|   |:||.|:|.||.
  Rat    89 KKLTKQDNLALVKSLN---LSLSKDGGKKFRY---------IENLEKCVKLEVLNLSYNLIAKIE 141

  Fly    65 GISGMKNLKVLSLARNNLKTLNGIEPLADTLEELWVSYNNIEKTKP--LESMKALRVFYISFNMI 127
            .:..:..|:.|:|:.|.:..:.|:|.:.: |::|.::.|.||....  .:.:|:|||..:..|.|
  Rat   142 KVDKLLRLRELNLSYNKISKIEGLENMCN-LQKLNLAGNEIEHIPGWFSKKLKSLRVLNLKGNKI 205

  Fly   128 KDWTEFMRMGVPPNLSEITFVGNPLNENMDQSAFTAEAVRRLPNMKKLDGEPV 180
            ....:..::....:|:.:|.:.||:   :....:....:..|.:::.|:|:||
  Rat   206 SSLQDVSKLKPLQDLTSLTLIDNPV---VALPHYLQFIIFHLRSLESLEGQPV 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10839	NP_001246039.1	LRR_RI	<37..129	CDD:238064	27/96 (28%)
		LRR_4	48..90	CDD:289563	14/44 (32%)
		leucine-rich repeat	50..71	CDD:275380	9/23 (39%)
		LRR_8	51..105	CDD:290566	17/56 (30%)
		leucine-rich repeat	72..94	CDD:275380	6/21 (29%)
		leucine-rich repeat	95..116	CDD:275380	5/22 (23%)
		leucine-rich repeat	117..141	CDD:275380	5/23 (22%)
		leucine-rich repeat	142..171	CDD:275380	5/28 (18%)
Cntrl	XP_006234114.1	PPP1R42	89..261	CDD:411060	45/183 (25%)
		leucine-rich repeat	100..119	CDD:275378	4/30 (13%)
		leucine-rich repeat	127..148	CDD:275380	7/20 (35%)
		leucine-rich repeat	149..170	CDD:275380	6/20 (30%)
		leucine-rich repeat	171..194	CDD:275380	5/22 (23%)
		leucine-rich repeat	195..219	CDD:275380	5/23 (22%)
		leucine-rich repeat	220..246	CDD:275380	5/28 (18%)
		PTZ00108	<267..535	CDD:240271
		SMC_prok_B	<438..1120	CDD:274008
		Drf_FH1	1238..>1300	CDD:399386
		SMC_prok_B	1396..2215	CDD:274008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810