DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10839 and Cntrl

DIOPT Version :9

Sequence 1:NP_001246039.1 Gene:CG10839 / 34944 FlyBaseID:FBgn0028858 Length:182 Species:Drosophila melanogaster
Sequence 2:NP_001366203.1 Gene:Cntrl / 26920 MGIID:1889576 Length:2334 Species:Mus musculus


Alignment Length:184 Identity:45/184 - (24%)
Similarity:92/184 - (50%) Gaps:23/184 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 KPTTLKDALAKWEDRNKQPAATATEIGLQFQYPPIEKMDPILNSLTECQK---LSLSSNMIEKIT 64
            |..|.:|.||..:..|   .:.:.:.|.:|:|         :.:|.:|.|   |:||.|:|.||.
Mouse    89 KKLTKQDNLALVKSLN---LSLSKDGGKKFRY---------IENLEKCVKLEVLNLSYNLIVKIE 141

  Fly    65 GISGMKNLKVLSLARNNLKTLNGIEPLADTLEELWVSYNNIEKTKPL---ESMKALRVFYISFNM 126
            .:..:..|:.|:|:.|.:..:.|:|.:.: |::|.::.|.||.. |:   :.:|:|||..:..|.
Mouse   142 KVDKLLRLRELNLSYNKISKIEGLENMCN-LQKLNLAGNEIEHI-PVWFAKKLKSLRVLNLKGNK 204

  Fly   127 IKDWTEFMRMGVPPNLSEITFVGNPLNENMDQSAFTAEAVRRLPNMKKLDGEPV 180
            |....:..::....:|:.:..:.||:   :....:....:..|.:::.|:|:||
Mouse   205 ISSLQDVSKLKPLQDLTSLVLIDNPV---VALPHYLQFIIFHLRSLESLEGQPV 255

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10839NP_001246039.1 LRR_RI <37..129 CDD:238064 28/97 (29%)
LRR_4 48..90 CDD:289563 14/44 (32%)
leucine-rich repeat 50..71 CDD:275380 9/23 (39%)
LRR_8 51..105 CDD:290566 17/56 (30%)
leucine-rich repeat 72..94 CDD:275380 6/21 (29%)
leucine-rich repeat 95..116 CDD:275380 6/23 (26%)
leucine-rich repeat 117..141 CDD:275380 5/23 (22%)
leucine-rich repeat 142..171 CDD:275380 4/28 (14%)
CntrlNP_001366203.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..70
PPP1R42 89..261 CDD:411060 45/184 (24%)
leucine-rich repeat 100..119 CDD:275378 4/30 (13%)
LRR 1 126..147 8/20 (40%)
leucine-rich repeat 127..148 CDD:275380 7/20 (35%)
LRR 2 148..169 6/20 (30%)
leucine-rich repeat 149..170 CDD:275380 6/20 (30%)
LRR 3 170..191 6/22 (27%)
leucine-rich repeat 171..194 CDD:275380 6/23 (26%)
LRR 4 194..215 5/20 (25%)
leucine-rich repeat 195..219 CDD:275380 5/23 (22%)
leucine-rich repeat 220..246 CDD:275380 4/28 (14%)
Smc <270..602 CDD:224117
Smc 440..>1134 CDD:224117
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 542..562
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 751..771
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1154..1198
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1213..1245
Drf_FH1 <1239..1310 CDD:399386
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1338..1360
SMC_prok_B 1407..2216 CDD:274008
Required for centrosome localization. /evidence=ECO:0000250 1951..2121
Sufficient for interaction with HOOK2. /evidence=ECO:0000250 1988..2334
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2291..2334
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0531
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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