DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10839 and R02F11.4

DIOPT Version :9

Sequence 1:	NP_001246039.1	Gene:	CG10839 / 34944	FlyBaseID:	FBgn0028858	Length:	182	Species:	Drosophila melanogaster
Sequence 2:	NP_504289.1	Gene:	R02F11.4 / 178871	WormBaseID:	WBGene00019842	Length:	630	Species:	Caenorhabditis elegans

Alignment Length:	198	Identity:	51/198 - (25%)
Similarity:	78/198 - (39%)	Gaps:	54/198 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 KQPAATATEI------GLQFQ-------YPPIEKMDPILNSLTECQ-------------KLSLSS 57
            |..||..:|:      |..||       :|..:.:|     ..:||             :|.|:.
Worm    70 KSFAAEYSEVKHLKISGNCFQKFTYIKLFPKCQIID-----ARDCQINKFIADFNYNLLELHLAR 129

  Fly    58 NMIEKITGISGMKNLKVLSLARNNLKTLNGIEPLAD----TLEELWVSYNNIEKTKPLESMKALR 118
            |.:::...:...:|||:|.|: |||     |||...    .||.|.:|.|.:.:...|....||:
Worm   130 NQLKETNQLGRFENLKILDLS-NNL-----IEPPVSFSLKNLEILNLSGNFLNEIPDLSKCVALQ 188

  Fly   119 VFYISFNMIKDWTEFMRMGVPPNLSEITFVGNPLNENMDQSAFTAEAVRRLPNMKKLD-----GE 178
            ...::.|.|.|.|...::..|.||..:....|.:.   |.|.|:.     |...|||:     |.
Worm   189 TISLADNKISDLTTITKLICPTNLKNLDISSNSIE---DLSQFSV-----LSTFKKLEEFVVAGN 245

  Fly   179 PVI 181
            |.|
Worm   246 PSI 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10839	NP_001246039.1	LRR_RI	<37..129	CDD:238064	27/108 (25%)
		LRR_4	48..90	CDD:289563	14/54 (26%)
		leucine-rich repeat	50..71	CDD:275380	5/33 (15%)
		LRR_8	51..105	CDD:290566	20/70 (29%)
		leucine-rich repeat	72..94	CDD:275380	10/25 (40%)
		leucine-rich repeat	95..116	CDD:275380	6/20 (30%)
		leucine-rich repeat	117..141	CDD:275380	6/23 (26%)
		leucine-rich repeat	142..171	CDD:275380	6/28 (21%)
R02F11.4	NP_504289.1	leucine-rich repeat	57..78	CDD:275380	3/7 (43%)
		LRR_RI	<118..245	CDD:238064	37/140 (26%)
		leucine-rich repeat	122..143	CDD:275380	3/20 (15%)
		LRR_8	143..197	CDD:290566	20/59 (34%)
		leucine-rich repeat	144..164	CDD:275380	10/25 (40%)
		LRR_4	163..205	CDD:289563	12/41 (29%)
		leucine-rich repeat	165..186	CDD:275380	6/20 (30%)
		leucine-rich repeat	187..211	CDD:275380	6/23 (26%)
		leucine-rich repeat	212..236	CDD:275380	6/31 (19%)
		leucine-rich repeat	237..256	CDD:275380	4/12 (33%)
		DUF2730	<480..557	CDD:287743
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810