DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10839 and K10D2.8

DIOPT Version :9

Sequence 1:	NP_001246039.1	Gene:	CG10839 / 34944	FlyBaseID:	FBgn0028858	Length:	182	Species:	Drosophila melanogaster
Sequence 2:	NP_001254924.1	Gene:	K10D2.8 / 13189483	WormBaseID:	WBGene00189952	Length:	335	Species:	Caenorhabditis elegans

Alignment Length:	178	Identity:	50/178 - (28%)
Similarity:	82/178 - (46%)	Gaps:	36/178 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 LQFQYPPIEKMDPILNSLTECQKLSLSSNMIEKITGISGMKNLKVLSLARNNLKTLNGIEPLA-- 92
            |:|....|:||:. |:.|...::|.|.:|.|.||.|:.||..||.|||..|.|:.:.|::.|:
Worm   142 LEFGDNRIQKMEN-LSHLVNLERLFLGANQIRKIEGLDGMAQLKELSLPGNALQIIEGLDTLSGL 205

  Fly    93 -------------------DTLEELWVSYNNIEKTKPLESMKALRVFYISFNMIKDWTEFMRMGV 138
                               ..|:.|.::.|.|||.:.:|..|.:....|..|.:..|.:..::..
Worm   206 KSISLAQNGIRKIDGLSGLTNLKSLDLNDNIIEKLENVEQFKGISSLMIRKNKLNCWQDVRQLKK 270

  Fly   139 PPNLSEITFVGNPLNENMDQSAFTAEAVRR------LPNMKKLDGEPV 180
            ..||:.:|...|||        ::::...|      ||::|.|||.|:
Worm   271 LENLTVLTMEMNPL--------YSSDYTYRNRVKEILPDVKLLDGFPI 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10839	NP_001246039.1	LRR_RI	<37..129	CDD:238064	33/112 (29%)
		LRR_4	48..90	CDD:289563	17/41 (41%)
		leucine-rich repeat	50..71	CDD:275380	9/20 (45%)
		LRR_8	51..105	CDD:290566	21/74 (28%)
		leucine-rich repeat	72..94	CDD:275380	9/42 (21%)
		leucine-rich repeat	95..116	CDD:275380	7/20 (35%)
		leucine-rich repeat	117..141	CDD:275380	3/23 (13%)
		leucine-rich repeat	142..171	CDD:275380	7/34 (21%)
K10D2.8	NP_001254924.1	leucine-rich repeat	30..50	CDD:275380
		LRR_4	49..90	CDD:289563
		leucine-rich repeat	51..72	CDD:275380
		LRR_8	71..127	CDD:290566
		LRR_4	71..113	CDD:289563
		leucine-rich repeat	73..94	CDD:275380
		LRR_4	94..134	CDD:289563
		leucine-rich repeat	95..116	CDD:275380
		LRR_4	116..157	CDD:289563	6/15 (40%)
		leucine-rich repeat	117..138	CDD:275380
		leucine-rich repeat	139..160	CDD:275380	7/18 (39%)
		LRR_4	160..199	CDD:289563	16/38 (42%)
		leucine-rich repeat	161..182	CDD:275380	9/20 (45%)
		LRR_8	182..235	CDD:290566	11/52 (21%)
		leucine-rich repeat	183..204	CDD:275380	9/20 (45%)
		LRR_4	205..245	CDD:289563	6/39 (15%)
		leucine-rich repeat	205..226	CDD:275380	0/20 (0%)
		leucine-rich repeat	252..273	CDD:275380	3/20 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810