DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10839 and cntrl

DIOPT Version :9

Sequence 1:	NP_001246039.1	Gene:	CG10839 / 34944	FlyBaseID:	FBgn0028858	Length:	182	Species:	Drosophila melanogaster
Sequence 2:	XP_004919852.2	Gene:	cntrl / 100270771	XenbaseID:	XB-GENE-959037	Length:	2448	Species:	Xenopus tropicalis

Alignment Length:	164	Identity:	43/164 - (26%)
Similarity:	78/164 - (47%)	Gaps:	24/164 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 ATEIGLQFQYPPIEKMDPILNSLTECQK---LSLSSNMIEKITGISGMKNLKVLSLARNNLKTLN 86
            |.|.|.:|::         :.:|.:|::   |:||.|:||||..:.....|:.|:||.|.:..:.
Frog   187 AKEGGKKFKF---------IENLEKCERLEVLNLSHNLIEKIEKLEKQIRLRELNLAYNKISKIE 242

  Fly    87 GIEPLADTLEELWVSYNNIEKT-----KPLESMKALRVFYISFNMIKDWTEFMRMGVPPNLSEIT 146
            ..|.: ..|::|.::.|.||..     |.|:|:.||.   :..|.|....:..|:....:|:.::
Frog   243 HFEHM-QNLKKLNLAGNEIEHIPVWVGKKLKSLTALN---LKENRISSLQDVSRLKPLKDLTTLS 303

  Fly   147 FVGNPLNENMDQSAFTAEAVRRLPNMKKLDGEPV 180
            ...||::.......:|   |..|.::..||.:||
Frog   304 LSDNPVSNLPHYRLYT---VFHLRSLNSLDAQPV 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10839	NP_001246039.1	LRR_RI	<37..129	CDD:238064	28/99 (28%)
		LRR_4	48..90	CDD:289563	14/44 (32%)
		leucine-rich repeat	50..71	CDD:275380	9/23 (39%)
		LRR_8	51..105	CDD:290566	17/56 (30%)
		leucine-rich repeat	72..94	CDD:275380	6/21 (29%)
		leucine-rich repeat	95..116	CDD:275380	8/25 (32%)
		leucine-rich repeat	117..141	CDD:275380	4/23 (17%)
		leucine-rich repeat	142..171	CDD:275380	6/28 (21%)
cntrl	XP_004919852.2	PPP1R42	197..340	CDD:411060	39/145 (27%)
		leucine-rich repeat	206..227	CDD:275378	8/20 (40%)
		leucine-rich repeat	228..249	CDD:275378	6/21 (29%)
		leucine-rich repeat	250..273	CDD:275378	7/22 (32%)
		leucine-rich repeat	274..298	CDD:275378	5/26 (19%)
		leucine-rich repeat	299..312	CDD:275378	3/12 (25%)
		SMC_prok_B	<498..1133	CDD:274008
		Smc	1399..2229	CDD:224117
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910