Protein Alignment CG18063 and MYO1A

DIOPT Version :10

• Sequence 1: NP_723944.2
• Gene: CG18063 / 34943
• FlyBaseID: FBgn0028856
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_005370.1
• Gene: MYO1A / 4640
• HGNCID: 7595
• Length: 1043
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 65/272 - (23%)
• Similarity: 100/272 - (36%)
• Gaps: 79/272 - (29%)

  Fly    60 ARTIQRYIHGWLVRENFRKLQKSAIIIQKWWRRFEAQKNLLYVAESALQSAVLAHYDKSATLIQT 124
            |..||:...||..|.:::.::||.|:|..|:|             ..:|.........|..|||.
Human   701 ATLIQKIYRGWRCRTHYQLMRKSQILISSWFR-------------GNMQKKCYGKIKASVLLIQA 752

  Fly   125 LYRGWWSRKHIFDLTMLKSVQIMLAKDLIHSLV-NYLHATKNSEMLPGIYTIRDSS------ICL 182
            ..|||.:||: :.........:.||..:..|:| .:|...||:  ||.. .:.|.:      .||
Human   753 FVRGWKARKN-YRKYFRSEAALTLADFIYKSMVQKFLLGLKNN--LPST-NVLDKTWPAAPYKCL 813

  Fly   183 ETLEELMATFGFRFYNANACYKMKETLS--MVAQSRKTFTAT--------SYFTDVPYPGFNDRG 237
            .|..:.:....:::    .|.:.::.||  .|...|:...|:        ||...||.|
Human   814 STANQELQQLFYQW----KCKRFRDQLSPKQVEILREKLCASELFKGKKASYPQSVPIP------ 868

  Fly   238 FCGPRQNSAMTLNAKDPEHYELIHIFLSGSRKIGMTTAKLEQKIANIAEENRLNMF-----IKRD 297
            |||.                   :|.|.|:.|:        ||:.. .||..:.|.     :.|.
Human   869 FCGD-------------------YIGLQGNPKL--------QKLKG-GEEGPVLMAEAVKKVNRG 905

  Fly   298 NKKKSFIKRIYL 309
            |.|.|  .||.|
Human   906 NGKTS--SRILL 915

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18063	NP_723944.2	IQ	78..99	CDD:197470	6/20 (30%)
MYO1A	NP_005370.1	MYSc_Myo1	22..681	CDD:276829
		Actin-binding. /evidence=ECO:0000255	571..593
		IQ	742..764	CDD:197470	9/22 (41%)
		Myosin_TH1	847..1042	CDD:461801	25/105 (24%)