DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4793 and Tmprss9

DIOPT Version :9

Sequence 1:	NP_723941.2	Gene:	CG4793 / 34941	FlyBaseID:	FBgn0028514	Length:	910	Species:	Drosophila melanogaster
Sequence 2:	XP_006513905.2	Gene:	Tmprss9 / 432478	MGIID:	3612246	Length:	1342	Species:	Mus musculus

Alignment Length:	369	Identity:	97/369 - (26%)
Similarity:	159/369 - (43%)	Gaps:	70/369 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 TGR---PIIDFRGLNNGN-----QGCESGQTCCPKTEILQYPVQAD----NQPLPTECG------ 87
            |||   |:.: |.|.:|:     ..|::||  |...|..:...:.|    :.....:||
Mouse   390 TGRCEGPVTE-RDLKSGHCPGNVFSCQNGQ--CVSKENPECDDRVDCSDESDEAQCDCGWQPAWR 451

  Fly    88 HVNRIGVGFTITNARDIAQKGELPWMVALLDSRSRLPLGGGSLITRDVVLTSS--TKTLEVPEKY 150
            ...||..|..       |..||.||.|:|.::...  ..|.::|....:::::  ....:.|.::
Mouse   452 SAGRIVGGVE-------AAPGEFPWQVSLRENHEH--FCGATIIGARWLVSAAHCFNEFQDPAQW 507

  Fly   151 LIVRAGEWDFESITEERAHEDVAIRKIVRHTNLSVENGANNAALLFLARPLKLDHHIGLICLP-- 213
             ..:||......  .|.:.....:.:|.:|.....:....:.|:|.|||||....::...|||
Mouse   508 -AAQAGSVHLSG--SEASAVRTRVLRIAKHPAYDADTADFDVAVLELARPLPFGRYVQPACLPAA 569

  Fly   214 ----PPNRNFIHNRCIVSGWGKKTALDNSYM---NILKKIELPLVDRSVCQTKLQGPYGKDFILD 271
                ||.:     :|::||||   .|...::   .:|:|..:.|:|:|:|.:.    ||..  |.
Mouse   570 THVFPPGK-----KCLISGWG---YLKEDFLVKPEVLQKATVELLDQSLCSSL----YGHS--LT 620

  Fly   272 NSLICAGGEPGK-DTCKGDGGAPLACPLQSDPNRYELLGIVNFGFGCG-GPLPAAYTDVSQIRSW 334
            :.::|||...|| |:|:||.|.||.|  :....|:.|.|||::|.||. ...|..||.|:::|.|
Mouse   621 DRMVCAGYLDGKVDSCQGDSGGPLVC--EEPSGRFFLAGIVSWGIGCAEARRPGVYTRVTRLRDW 683

  Fly   335 IDNCIQAEAVHYSPQLGNVGQSPAPLDRYIPNIGLETQNEVHSP 378
            |.....|..:...|.     .:|||.   .|:....|..|..:|
Mouse   684 ILEVTSAADMPVVPT-----ATPAPA---TPSTPWPTSPESWAP 719

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4793	NP_723941.2	Tryp_SPc	105..337	CDD:238113	70/244 (29%)
CG4793	NP_723941.2	Tryp_SPc	105..335	CDD:214473	68/242 (28%)
Tmprss9	XP_006513905.2	SEA	285..365	CDD:366610
		LDLa	407..442	CDD:238060	6/36 (17%)
		Tryp_SPc	455..684	CDD:214473	71/256 (28%)
		Tryp_SPc	756..984	CDD:214473
		Tryp_SPc	1085..1336	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910