DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4793 and proca

DIOPT Version :9

Sequence 1:	NP_723941.2	Gene:	CG4793 / 34941	FlyBaseID:	FBgn0028514	Length:	910	Species:	Drosophila melanogaster
Sequence 2:	NP_956650.1	Gene:	proca / 393327	ZFINID:	ZDB-GENE-060824-5	Length:	434	Species:	Danio rerio

Alignment Length:	304	Identity:	88/304 - (28%)
Similarity:	138/304 - (45%)	Gaps:	46/304 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 GNQGCESGQTCCPKTEI----LQYPVQA-DNQPLPTECGHVNRIGVGFTITNARDIAQKGELPWM 113
            |.|..::.:.|.||.:.    ::.|..| .|:|.|.....|....||          ::||.||.
Zfish   155 GYQLQDNSRKCTPKNDASCGQIRIPKSAYANKPKPVLQPWVMGGNVG----------KRGESPWQ 209

  Fly   114 VALLDSRSRLPLGGGSLITRDVVLTSSTKTLEVPEKYLIVRAGEWDFESITEERAHEDVAIRKIV 178
            ..:|:...|... ||.||..:.|||:: ..||...|: .||.|  |::....|.:...:.:::.:
Zfish   210 ALILNHLGRFHC-GGVLIDENWVLTAA-HCLETSSKF-SVRLG--DYQRFKFEGSEVTLPVKQHI 269

  Fly   179 RHTNLSVENGANNAALLFLARPLKLDHHIGLICLPPPN--RNFIHNR---CIVSGWGKKTALDNS 238
            .|...:.....|:.|||.|..|:|...:|...|||...  :..:|..   .|::||||......|
Zfish   270 SHPQYNPITVDNDIALLRLDGPVKFSTYILPACLPSLELAKRMLHRNGTVTIITGWGKNNQSATS 334

  Fly   239 YMNILKKIELPLVDRSVCQTKLQGPYGKDFILDNSLICAG--GEPGKDTCKGDGGAPLACPLQSD 301
            |.:.|..:|||:||...|...:...      |.::::|||  |:. ||.|:||.|.|:.....
Zfish   335 YNSTLHYVELPIVDNKECSRHMMNN------LSDNMLCAGVLGQV-KDACEGDSGGPMMTLFH-- 390

  Fly   302 PNRYELLGIVNFGFGCG-----GPLPAAYTDVSQIRSWIDNCIQ 340
             :.:.|:|:|::|.|||     |    .||.|:....|||:..|
Zfish   391 -DTWFLVGLVSWGEGCGQRDKLG----IYTKVASYLDWIDSVRQ 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4793	NP_723941.2	Tryp_SPc	105..337	CDD:238113	73/243 (30%)
CG4793	NP_723941.2	Tryp_SPc	105..335	CDD:214473	71/241 (29%)
proca	NP_956650.1	GLA	23..84	CDD:214503
		EGF_CA	85..119	CDD:238011
		FXa_inhibition	128..165	CDD:291342	2/9 (22%)
		Tryp_SPc	195..427	CDD:238113	77/260 (30%)
		Tryp_SPc	197..424	CDD:214473	73/255 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910