DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4793 and CG1299

DIOPT Version :9

Sequence 1:	NP_723941.2	Gene:	CG4793 / 34941	FlyBaseID:	FBgn0028514	Length:	910	Species:	Drosophila melanogaster
Sequence 2:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster

Alignment Length:	351	Identity:	105/351 - (29%)
Similarity:	163/351 - (46%)	Gaps:	57/351 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 KECVQ-----RNRCRIGTETGRPIIDFRGLNNGNQGCES--GQTCCPKTEILQYPVQADNQPLPT 84
            |||..     |:|.:..|     ..:|  |...|..|::  .|.|||..:.:.....|.:|.:|.
  Fly   178 KECASLLNELRSRSQDAT-----FANF--LRASNAVCQNKGTQVCCPTGQGITNTTPAPSQIVPK 235

  Fly    85 ECGHVNR------IGVGFTITNAR-----DIAQKGELPWMVALL--DSRSRLPLG-GGSLITRDV 135
            ....:.|      .|.|.|:...:     ::::||..|| :|||  |..|..|.. ||:|||...
  Fly   236 NTDEIPRRLLNVEEGCGSTVGYFKKIVGGEVSRKGAWPW-IALLGYDDPSGSPFKCGGTLITARH 299

  Fly   136 VLTSSTKTLEVPEKYLIVRAGEWDFESITEERAHEDVAIRKIVRHTNLSVENGANNAALLFLARP 200
            |||::..   :.:....||.||.|..:.| |..|.|:.|.:.|.|.:.:..||.::.|:|:|.|.
  Fly   300 VLTAAHC---IRQDLQFVRLGEHDLSTDT-ETGHVDINIARYVSHPDYNRRNGRSDMAILYLERN 360

  Fly   201 LKLDHHIGLICLPPP----NRNFIHNRCIVSGWGKKTALDNSYMNILKKIELPLVDRSVCQTKLQ 261
            ::....|..||||..    .::::.....|:||| ||........:|.::::|:.|..||...
  Fly   361 VEFTSKIAPICLPHTANLRQKSYVGYMPFVAGWG-KTMEGGESAQVLNELQIPIYDNKVCVQS-- 422

  Fly   262 GPYGKD---FI---LDNSLICAGG-EPGKDTCKGDGGAPLACPLQSDPN----RYELLGIVNFGF 315
              |.|:   |.   .|.:::|||. ..|||||:||.|.||..|   :|.    |:.|:|:|::|.
  Fly   423 --YAKEKRYFSADQFDKAVLCAGVLSGGKDTCQGDSGGPLMLP---EPYQGQLRFYLIGVVSYGI 482

  Fly   316 GCGGP-LPAAYTDVSQIRSWIDNCIQ 340
            ||..| :|..|:.......||...:|
  Fly   483 GCARPNVPGVYSSTQYFMDWIIQQVQ 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4793	NP_723941.2	Tryp_SPc	105..337	CDD:238113	83/250 (33%)
CG4793	NP_723941.2	Tryp_SPc	105..335	CDD:214473	81/248 (33%)
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	11/44 (25%)
		Tryp_SPc	260..503	CDD:214473	81/255 (32%)
		Tryp_SPc	261..503	CDD:238113	81/254 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910