DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4793 and Tmprss11b

DIOPT Version :9

Sequence 1:	NP_723941.2	Gene:	CG4793 / 34941	FlyBaseID:	FBgn0028514	Length:	910	Species:	Drosophila melanogaster
Sequence 2:	NP_001004020.1	Gene:	Tmprss11b / 365265	RGDID:	1303278	Length:	420	Species:	Rattus norvegicus

Alignment Length:	294	Identity:	79/294 - (26%)
Similarity:	132/294 - (44%)	Gaps:	36/294 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 NNGNQGCESGQTCCPKTEILQYPVQADNQPLPTECGHVNRIGVGFTITNARDIAQKGELPWMVAL 116
            |:|:...:.|.  ...|||.:  |.|: :.:...||...|:...:........|||||.||..:|
  Rat   147 NSGSLTTDPGS--LKLTEITK--VDAE-KIINNRCGRRPRMSATYDRITGGSTAQKGEWPWQASL 206

  Fly   117 -LDSRSRLPLGGGSLITRDVVLTSSTKTLEVPE-KYLIVRAGEWDFESITEERAHEDVAIRKIVR 179
             ::.:...   |.|||....:||::...|.... |.|.|..|    ..:|.  |:....:.:::.
  Rat   207 RVNGKHHC---GASLIGERFLLTAAHCFLRTNNPKNLTVSFG----TRVTP--AYMQHYVEEVII 262

  Fly   180 HTNLSVENGANNAALLFLARPLKLDHHIGLICLP------PPNRNFIHNRCIVSGWGKKTALDNS 238
            |.:.......::.|::.|...:...:.:..:|||      ||...     .:|:|||..:....|
  Rat   263 HEDYVKGQHHDDVAIIKLTEKVSFRNDVHRVCLPEATQVFPPGEG-----VVVTGWGSLSYNGKS 322

  Fly   239 YMNILKKIELPLVDRSVCQTKLQGPYGKDFILDNSLICAGGEPG-KDTCKGDGGAPLACPLQSDP 302
            .: :|:|..:.::|.:.|.:  :..|| ..|:| :::|||...| .|.|:||.|.||..|...|
  Rat   323 PL-LLQKASIKIIDTNACNS--EEAYG-GRIMD-TMLCAGYMEGYVDACQGDSGGPLVHPNSRD- 381

  Fly   303 NRYELLGIVNFGFGCGG-PLPAAYTDVSQIRSWI 335
             .:.|:|||::|..||. ..|..|..|:..|.||
  Rat   382 -IWYLVGIVSWGHECGRVNKPGVYMRVTSYRDWI 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4793	NP_723941.2	Tryp_SPc	105..337	CDD:238113	68/241 (28%)
CG4793	NP_723941.2	Tryp_SPc	105..335	CDD:214473	66/239 (28%)
Tmprss11b	NP_001004020.1	SEA	50..144	CDD:279699
		Tryp_SPc	188..414	CDD:214473	66/246 (27%)
		Tryp_SPc	189..417	CDD:238113	68/247 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910