DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4793 and OVCH2

DIOPT Version :9

Sequence 1:	NP_723941.2	Gene:	CG4793 / 34941	FlyBaseID:	FBgn0028514	Length:	910	Species:	Drosophila melanogaster
Sequence 2:	XP_016873148.1	Gene:	OVCH2 / 341277	HGNCID:	29970	Length:	569	Species:	Homo sapiens

Alignment Length:	306	Identity:	79/306 - (25%)
Similarity:	129/306 - (42%)	Gaps:	65/306 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 QKGELPWMVALLDSRSRLPLGGGSLITRDVVLTSS--------TKTLEVPEKYLIVRAGEWDFES 162
            :||..||.|:|...:..  :.|||:::...|:|::        ..||.       |.|||:|...
Human    63 EKGSYPWQVSLKQRQKH--ICGGSIVSPQWVITAAHCIANRNIVSTLN-------VTAGEYDLSQ 118

  Fly   163 ITEERAHEDVAIRKIVRHTNLSVENGAN-NAALLFLARPLKLDHHIGLICLPPPNRNFIHN-RCI 225
              .:...:.:.|..::.|.:.|.:...: :.|||.:|...:..|.:|.||||.....|... .|.
Human   119 --TDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELREQFEAGFICT 181

  Fly   226 VSGWGKKTALDNSYMNILKKIELPLVDRSVCQT---KLQGPY-GKDFILDNSLICAG-GEPGKDT 285
            .:|||:.|. ......:|:::.||::....|..   .|:.|. ||.|      :|.| .:.|:|.
Human   182 TAGWGRLTE-GGVLSQVLQEVNLPILTWEECVAALLTLKRPISGKTF------LCTGFPDGGRDA 239

  Fly   286 CKGDGGAPLACPLQSDPNRYELLGIVNFGFGCG------------GPLPAAYTDVSQIRSWIDNC 338
            |:||.|..|.|  ::....:.|.|:.::|.|||            |. |..:||:|::..||
Human   240 CQGDSGGSLMC--RNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGS-PGIFTDISKVLPWI--- 298

  Fly   339 IQAEAVHYSPQLGNVGQSPAPLDRYIPNIGLETQNEVHSPVQGSLH 384
                  |...|.||..:|        .......|:.:.|..:|.||
Human   299 ------HEHIQTGNRRKS--------SRAWCSEQDVIVSGAEGKLH 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4793	NP_723941.2	Tryp_SPc	105..337	CDD:238113	69/257 (27%)
CG4793	NP_723941.2	Tryp_SPc	105..335	CDD:214473	67/255 (26%)
OVCH2	XP_016873148.1	Tryp_SPc	55..298	CDD:214473	67/255 (26%)
		Tryp_SPc	56..301	CDD:238113	70/267 (26%)
		CUB	320..424	CDD:238001	4/11 (36%)
		CUB	435..546	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910