DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4793 and prss60.3

DIOPT Version :9

Sequence 1:	NP_723941.2	Gene:	CG4793 / 34941	FlyBaseID:	FBgn0028514	Length:	910	Species:	Drosophila melanogaster
Sequence 2:	XP_002662541.2	Gene:	prss60.3 / 335152	ZFINID:	ZDB-GENE-030131-7092	Length:	330	Species:	Danio rerio

Alignment Length:	292	Identity:	86/292 - (29%)
Similarity:	128/292 - (43%)	Gaps:	43/292 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 TC-------CPKTEILQYPVQADNQPLPTE-CGHVNRIGVGFTITNARDIAQKGELPWMVALLDS 119
            ||       |.|..:.|..| ....||.|. .|.||              |..|..||.|:|...
Zfish     7 TCATLTLLICVKGSLSQLNV-CGQAPLNTRIVGGVN--------------ASPGSWPWQVSLHSP 56

  Fly   120 RSRLPLGGGSLITRDVVLTSSTKTLEVPEKYLIVRAGEWDFESITEERAHEDVAIRKIVRHTNLS 184
            :......|||||:.:.|||::.....|.|..|:|..|....:.|.......:||  |...|::.:
Zfish    57 KYGGHFCGGSLISSEWVLTAAHCLSGVSETTLVVYLGRRTQQGINIYETSRNVA--KSFVHSSYN 119

  Fly   185 VENGANNAALLFLARPLKLDHHIGLICLPPPNRNF-IHNRCIVSGWGK-KTALDNSYMNILKKIE 247
            .....|:.|||.|:..:...::|..:||...|..: ......::|||. :..::.....||::..
Zfish   120 SNTNDNDIALLRLSSAVTFTNYIRPVCLAAQNSVYSAGTSSWITGWGDIQAGVNLPAPGILQETM 184

  Fly   248 LPLVDRSVCQTKLQGPYGKDFILDNSLICAG-GEPGKDTCKGDGGAPLA---CPLQSDPNRYELL 308
            :|:|....|...|    |...: .|::|||| .:.|||||:||.|.|:.   |.:      :...
Zfish   185 IPVVANDRCNALL----GSGTV-TNNMICAGLTQGGKDTCQGDSGGPMVTRLCTV------WVQA 238

  Fly   309 GIVNFGFGCGGP-LPAAYTDVSQIRSWIDNCI 339
            ||.::|:||..| .|..||.|||.:|||.:.|
Zfish   239 GITSWGYGCADPNSPGVYTRVSQYQSWISSKI 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4793	NP_723941.2	Tryp_SPc	105..337	CDD:238113	73/238 (31%)
CG4793	NP_723941.2	Tryp_SPc	105..335	CDD:214473	71/236 (30%)
prss60.3	XP_002662541.2	Tryp_SPc	36..269	CDD:238113	76/259 (29%)
prss60.3	XP_002662541.2	Somatomedin_B	294..328	CDD:321959
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587622
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930