DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4793 and plg

DIOPT Version :9

Sequence 1:	NP_723941.2	Gene:	CG4793 / 34941	FlyBaseID:	FBgn0028514	Length:	910	Species:	Drosophila melanogaster
Sequence 2:	NP_958880.2	Gene:	plg / 322691	ZFINID:	ZDB-GENE-030131-1411	Length:	818	Species:	Danio rerio

Alignment Length:	296	Identity:	82/296 - (27%)
Similarity:	132/296 - (44%)	Gaps:	62/296 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 CESGQTCCPKTEILQYPVQADNQPLPTECGHVNRIGVGFTITNARDIAQKGELPWMVALLDSRSR 122
            |||.:...|.|:             |..|  ..||..|.       :::....||.:: |.:|.:
Zfish   570 CESLKCGQPATK-------------PKRC--FGRIVGGC-------VSKPHSWPWQIS-LRTRGK 611

  Fly   123 LPLGGGSLITRDVVLTSS--TKTLEVPEKYLIVRAGEWDFESITEERAHE----DVAIRKIVRHT 181
            :...||:||....|:|::  .:..:.|..|.|:.       .|..|||.|    :..:.||::..
Zfish   612 IHFCGGTLIDPQWVVTAAHCLERSDSPSAYKIML-------GIHTERATESSKQERDVTKIIKGP 669

  Fly   182 NLSVENGANNAALLFLARPLKLDHHIGLICLPPPNRNFI---HNRCIVSGWGKKTALDNSYMNIL 243
                  ...:.|||.|.||..::..:..:||  |.:::|   :..|.|:|||:  ..|......|
Zfish   670 ------AGTDIALLKLDRPALINDKVSPVCL--PEKDYIVPSNTECYVTGWGE--TQDTGGEGYL 724

  Fly   244 KKIELPLVDRSVCQ--TKLQGPYGKDFILDNSLICAGG-EPGKDTCKGDGGAPLACPLQSDPNRY 305
            |:...|:::..||.  :.|.|.     :.|:.: |||. |.|.|:|:||.|.||.|..|   |.:
Zfish   725 KETGFPVIENKVCNRPSFLNGR-----VKDHEM-CAGNIEGGNDSCQGDSGGPLVCYAQ---NTF 780

  Fly   306 ELLGIVNFGFGCGGPL-PAAYTDVSQIRSWIDNCIQ 340
            .|.|:.::|.||...: |..||.||:...||:..|:
Zfish   781 VLQGVTSWGLGCANAMKPGVYTRVSKFVDWIERSIK 816

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4793	NP_723941.2	Tryp_SPc	105..337	CDD:238113	71/244 (29%)
CG4793	NP_723941.2	Tryp_SPc	105..335	CDD:214473	69/242 (29%)
plg	NP_958880.2	PAN_AP_HGF	31..104	CDD:238532
		KR	109..190	CDD:214527
		KR	190..270	CDD:214527
		KR	281..361	CDD:214527
		Kringle	376..453	CDD:306546
		KR	490..572	CDD:214527	1/1 (100%)
		Tryp_SPc	589..813	CDD:238113	73/257 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910