DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4793 and Tmprss11b

DIOPT Version :9

Sequence 1:	NP_723941.2	Gene:	CG4793 / 34941	FlyBaseID:	FBgn0028514	Length:	910	Species:	Drosophila melanogaster
Sequence 2:	NP_795998.2	Gene:	Tmprss11b / 319875	MGIID:	2442893	Length:	416	Species:	Mus musculus

Alignment Length:	281	Identity:	74/281 - (26%)
Similarity:	126/281 - (44%)	Gaps:	40/281 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 TEILQYPVQADNQPLPTECGHVNRIGVGFTITNARDIAQKGELPWMVALLDSRSRLPLGGGSLIT 132
            |||.:  |.|: :.:...||...|:...:........|.|||.||..:|..:...  ..|.|||.
Mouse   157 TEISK--VDAE-KIINNRCGRRPRMSATYDRITGGSTAHKGEWPWQASLRVNGKH--YCGASLIG 216

  Fly   133 RDVVLTSS-----TKTLEVPEKYLIVRAGEWDFESITEERAHEDVAIRKIVRHTNLSVENGANNA 192
            ...:||::     |..    .|.|.|..|    ..:|.  |:...::::|:.|.:.......::.
Mouse   217 ERFLLTAAHCFQGTNN----PKNLTVSFG----TRVTP--AYMQHSVQEIIIHEDYVKGEHHDDV 271

  Fly   193 ALLFLARPLKLDHHIGLICLP------PPNRNFIHNRCIVSGWGKKTALDNSYMNILKKIELPLV 251
            |::.|...:..::.:..:|||      ||...     .:|:|||..:....|.: :|:|..:.::
Mouse   272 AVIKLTEKVSFNNDVHRVCLPESTQIFPPGEG-----VVVTGWGSFSYNGKSPL-LLQKASIKII 330

  Fly   252 DRSVCQTKLQGPYGKDFILDNSLICAGGEPGK-DTCKGDGGAPLACPLQSDPNRYELLGIVNFGF 315
            |.:.|.:  :..||...:  ::::|||...|. |.|:||.|.||..|...|  .:.|:|||::|.
Mouse   331 DTNTCNS--EEAYGGRIV--DTMLCAGYLEGSIDACQGDSGGPLVHPNSRD--IWYLVGIVSWGH 389

  Fly   316 GCGG-PLPAAYTDVSQIRSWI 335
            .||. ..|..|..|:..|:||
Mouse   390 ECGRVNKPGVYMRVTSYRNWI 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4793	NP_723941.2	Tryp_SPc	105..337	CDD:238113	66/244 (27%)
CG4793	NP_723941.2	Tryp_SPc	105..335	CDD:214473	64/242 (26%)
Tmprss11b	NP_795998.2	SEA	46..140	CDD:279699
		Tryp_SPc	184..410	CDD:214473	64/249 (26%)
		Tryp_SPc	185..413	CDD:238113	66/250 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910