DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4793 and Tmprss9

DIOPT Version :9

Sequence 1:	NP_723941.2	Gene:	CG4793 / 34941	FlyBaseID:	FBgn0028514	Length:	910	Species:	Drosophila melanogaster
Sequence 2:	NP_001382445.1	Gene:	Tmprss9 / 314636	RGDID:	1309581	Length:	1095	Species:	Rattus norvegicus

Alignment Length:	442	Identity:	104/442 - (23%)
Similarity:	179/442 - (40%)	Gaps:	111/442 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 TGR---PIIDFRGLNNGN-----QGCESGQTCCPKTEILQYPVQAD----NQPLPTECG------ 87
            |||   |:.: |.|.:|:     ..|::.|  |...|..:...:.|    :.....:||
  Rat   173 TGRCEGPVTE-RDLKSGHCPGNAFSCQNSQ--CVSKENPECDDRVDCSDGSDEAQCDCGWQPAWR 234

  Fly    88 HVNRIGVGFTITNARDIAQKGELPWMVALLDSRSRLPLGGGSLITRDVVLTSS--TKTLEVPEKY 150
            ...||..|..       |..||.||.|:|.::...  ..|.::|....:::::  ....:.|.::
  Rat   235 SAGRIVGGAE-------AAPGEFPWQVSLRENHEH--FCGATIIGARWLVSAAHCFNEFQDPAQW 290

  Fly   151 LIVRAGEWDFESITEERAHEDVAIRKIVRHTNLSVENGANNAALLFLARPLKLDHHIGLICLP-- 213
             ..:||......  .|.:.....:.:|.:|...:.:....:.|:|.|||||....::...|||
  Rat   291 -AAQAGSVHLSG--SEASAVRARVLRIAKHPAYNADTADFDVAVLELARPLPFGRYVQPACLPAA 352

  Fly   214 ----PPNRNFIHNRCIVSGWGKKTALDNSYM---NILKKIELPLVDRSVCQTKLQGPYGKDFILD 271
                ||.:     :|::||||   .|...::   .:|:|..:.|:|:::|.:.    ||..  |.
  Rat   353 THVFPPRK-----KCLISGWG---YLKEDFLVKPEVLQKATVELLDQNLCSSL----YGHS--LT 403

  Fly   272 NSLICAGGEPGK-DTCKGDGGAPLACPLQSDPNRYELLGIVNFGFGCG-GPLPAAYTDVSQIRSW 334
            :.::|||...|| |:|:||.|.||.|  :....|:.|.|:|::|.||. ...|..||.|:::|.|
  Rat   404 DRMVCAGYLDGKVDSCQGDSGGPLVC--EEPSGRFFLAGVVSWGIGCAEARRPGVYTRVTRLRDW 466

  Fly   335 IDNCIQAEAVHYSPQLGNVGQSPAPL----------DRYIPNIGLETQNEVHSPVQGSLH----- 384
            |.....:......|.     ::|||:          :..:||   .|.....:|....||
  Rat   467 ILEVTSSADTPVVPT-----EAPAPITPSTPWPTSPESRVPN---TTAKPTVAPTPAPLHPSTAA 523

  Fly   385 ---------------NVVYQTGGVGYIRG-------MGQGTA-FQGPVQVGE 413
                           .:|   ||:..:.|       :.:|:. |.|...||:
  Rat   524 KPQECGARPAMDKPTRIV---GGISAVSGEVPWQASLKEGSRHFCGATVVGD 572

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4793	NP_723941.2	Tryp_SPc	105..337	CDD:238113	68/244 (28%)
CG4793	NP_723941.2	Tryp_SPc	105..335	CDD:214473	66/242 (27%)
Tmprss9	NP_001382445.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910