DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4793 and Plau

DIOPT Version :9

Sequence 1:	NP_723941.2	Gene:	CG4793 / 34941	FlyBaseID:	FBgn0028514	Length:	910	Species:	Drosophila melanogaster
Sequence 2:	NP_037217.3	Gene:	Plau / 25619	RGDID:	3343	Length:	432	Species:	Rattus norvegicus

Alignment Length:	400	Identity:	98/400 - (24%)
Similarity:	154/400 - (38%)	Gaps:	112/400 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 CGGSMAKECVQRN----RCRIGTET-GRPIIDFR-------------------GLNNGNQGCESG 61
            |....:|.|...|    |.:..|:| |||.:.:.                   ||...|. |.:.
  Rat    62 CEIDTSKTCYHGNGQSYRGKANTDTKGRPCLAWNSPAVLQQTYNAHRSDALSLGLGKHNY-CRNP 125

  Fly    62 QT-----CCPKTEILQYPVQA-------DNQPLPT------ECG------HVNRIGVGFTITNAR 102
            ..     |..:..:.|:..:.       ..:|..|      :||      ....:|..||:...:
  Rat   126 DNQRRPWCYVQIGLKQFVQECMVQDCSLSKKPSSTVDQQGFQCGQKALRPRFKIVGGEFTVVENQ 190

  Fly   103 DIAQKGELPWMVAL-LDSRSRLPLG---GGSLITRDVVLTSSTKTLEVP--EKYLI--------- 152
                    ||..|: |.::...|..   |||||:...|.:::...:..|  |:|::
  Rat   191 --------PWFAAIYLKNKGGSPPSFKCGGSLISPCWVASATHCFVNQPKKEEYVVYLGQSKRNS 247

  Fly   153 VRAGEWDFESITEERAHEDVAIRKIVRHTNLSVENGA--NNAALLFL-------ARPLKLDHHIG 208
            ...||..||            :.:::.|.:.|.|..|  |:.|||.:       |:|.:.   |.
  Rat   248 YNPGEMKFE------------VEQLILHEDFSDETLAFHNDIALLKIRTSTGQCAQPSRT---IQ 297

  Fly   209 LICLPPPNRNF----IHNRCIVSGWGKKTALDNSYMNILKKIELPLVDRSVCQTKLQGPYGKDFI 269
            .|||||   .|    ..:.|.::|:|:::|.|..|...||...:.::....|  |....||.:
  Rat   298 TICLPP---RFGDAPFGSDCEITGFGQESATDYFYPKDLKMSVVKIISHEQC--KQPHYYGSE-- 355

  Fly   270 LDNSLICAGGEPGK-DTCKGDGGAPLACPLQSDPNRYELLGIVNFGFGCGGP-LPAAYTDVSQIR 332
            ::..::||.....| |:|.||.|.||.|.:...|.   |.|||::|.||... .|..||.||...
  Rat   356 INYKMLCAADPEWKTDSCSGDSGGPLICNIDGRPT---LSGIVSWGSGCAEKNKPGVYTRVSYFL 417

  Fly   333 SWIDNCIQAE 342
            :||.:.|..|
  Rat   418 NWIQSHIGEE 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4793	NP_723941.2	Tryp_SPc	105..337	CDD:238113	73/261 (28%)
CG4793	NP_723941.2	Tryp_SPc	105..335	CDD:214473	71/259 (27%)
Plau	NP_037217.3	Binds urokinase plasminogen activator surface receptor	34..57
		KR	67..152	CDD:238056	15/85 (18%)
		Connecting peptide	152..178		4/25 (16%)
		Tryp_SPc	178..420	CDD:214473	74/274 (27%)
		Tryp_SPc	179..423	CDD:238113	76/276 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910