DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4793 and Tmprss3

DIOPT Version :9

Sequence 1:	NP_723941.2	Gene:	CG4793 / 34941	FlyBaseID:	FBgn0028514	Length:	910	Species:	Drosophila melanogaster
Sequence 2:	NP_001157248.1	Gene:	Tmprss3 / 140765	MGIID:	2155445	Length:	475	Species:	Mus musculus

Alignment Length:	292	Identity:	79/292 - (27%)
Similarity:	128/292 - (43%)	Gaps:	38/292 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 QGCESGQTCCPKTEILQYPVQADNQPLPTECGHVNRIGVGFTITNARDIAQKGELPWMVALLDSR 120
            :||.||.....|.               :.||  .|.|....|... :::...:.||.|:|  ..
Mouse   214 EGCTSGHVVTLKC---------------SACG--TRTGYSPRIVGG-NMSSLTQWPWQVSL--QF 258

  Fly   121 SRLPLGGGSLITRDVVLTSSTKTLEV--PEKYLIVRAGEWDFESITEERAHEDVAIRKIVRHTNL 183
            ....|.|||:||...::|::....::  |:.: .|:.|   ..|:.:......: :.||:.|:..
Mouse   259 QGYHLCGGSIITPLWIVTAAHCVYDLYHPKSW-TVQVG---LVSLMDSPVPSHL-VEKIIYHSKY 318

  Fly   184 SVENGANNAALLFLARPLKLDHHIGLICLPPPNRNFIHNR-CIVSGWGKKTALDNSYMNILKKIE 247
            ..:...|:.||:.|:.||..|..|..||||....||...: |..|||| .|........:|....
Mouse   319 KPKRLGNDIALMKLSEPLTFDETIQPICLPNSEENFPDGKLCWTSGWG-ATEDGGDASPVLNHAA 382

  Fly   248 LPLVDRSVCQTKLQGPYGKDFILDNSLICAGG-EPGKDTCKGDGGAPLACPLQSDPNRYELLGIV 311
            :||:...:|..:  ..||.  |:..|::|||. :.|.|:|:||.|.||.|   .:...::|:|..
Mouse   383 VPLISNKICNHR--DVYGG--IISPSMLCAGYLKGGVDSCQGDSGGPLVC---QERRLWKLVGAT 440

  Fly   312 NFGFGCGG-PLPAAYTDVSQIRSWIDNCIQAE 342
            :||.||.. ..|..||.::....||...::.:
Mouse   441 SFGIGCAEVNKPGVYTRITSFLDWIHEQLERD 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4793	NP_723941.2	Tryp_SPc	105..337	CDD:238113	69/236 (29%)
CG4793	NP_723941.2	Tryp_SPc	105..335	CDD:214473	67/234 (29%)
Tmprss3	NP_001157248.1	LDLa	96..129	CDD:238060
		SRCR_2	134..233	CDD:292133	7/35 (20%)
		Tryp_SPc	238..465	CDD:214473	68/242 (28%)
		Tryp_SPc	239..468	CDD:238113	70/244 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910