DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4793 and F2

DIOPT Version :9

Sequence 1:	NP_723941.2	Gene:	CG4793 / 34941	FlyBaseID:	FBgn0028514	Length:	910	Species:	Drosophila melanogaster
Sequence 2:	NP_034298.1	Gene:	F2 / 14061	MGIID:	88380	Length:	618	Species:	Mus musculus

Alignment Length:	265	Identity:	84/265 - (31%)
Similarity:	124/265 - (46%)	Gaps:	47/265 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 AQKGELPWMVALLDSRSRLPLGGGSLITRDVVLTSSTKTLEVP------EKYLIVRAGEWDFESI 163
            |:||..||.|.|.....:..|.|.|||:...|||::...|..|      |..|:||.|:   .|.
Mouse   367 AEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLLVRIGK---HSR 428

  Fly   164 TE-ERAHEDVA-IRKIVRHTNLS-VENGANNAALLFLARPLKLDHHIGLICLPPPN------RNF 219
            |. ||..|.:: :.||..|...: .||...:.|||.|.:|:....:|..:|||...      |..
Mouse   429 TRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVCLPDKQTVTSLLRAG 493

  Fly   220 IHNRCIVSGWGK-----KTALDNSYMNILKKIELPLVDRSVCQ--TKLQGPYGKDFILDNSLICA 277
            ...|  |:|||.     .|.::....::|:.:.||:|:|.||:  |:::       |.|| :.||
Mouse   494 YKGR--VTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTRIR-------ITDN-MFCA 548

  Fly   278 GGEPGK----DTCKGDGGAPLACPLQSDP--NRYELLGIVNFGFGCG--GPLPAAYTDVSQIRSW 334
            |.:...    |.|:||.|.|.   :...|  ||:..:|||::|.||.  |.. ..||.|.:::.|
Mouse   549 GFKVNDTKRGDACEGDSGGPF---VMKSPFNNRWYQMGIVSWGEGCDRKGKY-GFYTHVFRLKRW 609

  Fly   335 IDNCI 339
            |...|
Mouse   610 IQKVI 614

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4793	NP_723941.2	Tryp_SPc	105..337	CDD:238113	83/261 (32%)
CG4793	NP_723941.2	Tryp_SPc	105..335	CDD:214473	81/259 (31%)
F2	NP_034298.1	GLA	25..89	CDD:214503
		KR	107..189	CDD:214527
		KR	213..295	CDD:214527
		Thrombin_light	313..360	CDD:286482
		Tryp_SPc	360..610	CDD:214473	81/259 (31%)
		Tryp_SPc	361..613	CDD:238113	83/262 (32%)
		High affinity receptor-binding region which is also known as the TP508 peptide. /evidence=ECO:0000250	548..570		8/24 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910