DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4793 and AgaP_AGAP001366

DIOPT Version :9

Sequence 1:	NP_723941.2	Gene:	CG4793 / 34941	FlyBaseID:	FBgn0028514	Length:	910	Species:	Drosophila melanogaster
Sequence 2:	XP_321777.4	Gene:	AgaP_AGAP001366 / 1281814	VectorBaseID:	AGAP001366	Length:	563	Species:	Anopheles gambiae

Alignment Length:	375	Identity:	86/375 - (22%)
Similarity:	137/375 - (36%)	Gaps:	81/375 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 KECVQRNRCRIGTETGRPIIDFRGLNNGNQGCESGQTCCPKTEILQYPVQADN-----QPL--PT 84
            ::.:...|....|.|.|||.:.|..|..:|.....:...|...:...|:.||.     .|:  .|
Mosquito   200 RQRIANRRITTTTTTYRPIAEERIWNQPSQRSIPSEPTSPPKRVSTVPLIADKGFTTLAPIARST 264

  Fly    85 ECGHVNR------------------IG------------VGFTITNAR------DIAQKGELPWM 113
            ..|..||                  .|            .|..:..|.      .::::|:.||.
Mosquito   265 TAGGTNRDQYFAGDYAFLQHESTPKAGQTHYINKYEGDICGTVVPKANPLVTHGTVSERGQFPWH 329

  Fly   114 VALLDSRSRLP----LGGGSLITRDVVLTSS-TKTLEVPEK-----YLIVRAGEWDFESITEERA 168
            .||.  ||.:.    |.|.:||:|...:|:: ..|||...|     .|::..|:.|...  ....
Mosquito   330 GALY--RSTVTELKYLCGATLISRRASITAAHCVTLEKSSKPVDAGSLLLYFGKIDLSK--WNGP 390

  Fly   169 HEDVAIRKIVRHTNLSVENGANNAALLFLARPLKLDHHIGLICL---PPPNRNFIHNRCIVSGWG 230
            .||..||.|........|...|:.|:|.|...:|..:.:..:||   ....:..|:....|.|||
Mosquito   391 EEDAQIRSIHIPAQYQHERFFNDIAVLVLKEDIKYSNFVRPVCLWNFDDDYKTLINKIGFVPGWG 455

  Fly   231 -KKTALDNSYMNILKKIELPLVDRSVCQTKLQGPYGKDF---ILDNSLICAGGEPGKDTCKGDGG 291
             .:..|.:|.::.   .::|:|....|...     .:||   :..::..|||.:.|...|.||.|
Mosquito   456 YNEHGLVSSRLSF---AQMPVVAHETCIWS-----NRDFFSKVTSDTSFCAGFKNGTSVCNGDSG 512

  Fly   292 APLACPLQSDPNRYELLGIVNFG------FGCGGPLPAAYTDVSQIRSWI 335
            ..:   :....|.:.|.|||:..      |.|.......:||.::..|||
Mosquito   513 GGM---VFKHNNLWYLRGIVSVSAALQDRFHCDSKHYVVFTDAAKFTSWI 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4793	NP_723941.2	Tryp_SPc	105..337	CDD:238113	65/254 (26%)
CG4793	NP_723941.2	Tryp_SPc	105..335	CDD:214473	63/252 (25%)
AgaP_AGAP001366	XP_321777.4	GD_N	15..124	CDD:292649
		Tryp_SPc	315..560	CDD:238113	65/260 (25%)
		Tryp_SPc	315..559	CDD:214473	63/258 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910