DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4793 and AgaP_AGAP011669

DIOPT Version :9

Sequence 1:	NP_723941.2	Gene:	CG4793 / 34941	FlyBaseID:	FBgn0028514	Length:	910	Species:	Drosophila melanogaster
Sequence 2:	XP_320844.4	Gene:	AgaP_AGAP011669 / 1280970	VectorBaseID:	AGAP011669	Length:	576	Species:	Anopheles gambiae

Alignment Length:	314	Identity:	76/314 - (24%)
Similarity:	129/314 - (41%)	Gaps:	52/314 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 QGCESGQTCCPKTEILQYPVQADNQPLPTECGHVNRIGVGFTITNARDIAQKGELPWMVALL--- 117
            :|.|:..||..:..:.||                       .|.|..| |:.|..||.|||.
Mosquito    22 RGQENHLTCGKRKVVSQY-----------------------LIHNGID-AKAGHWPWHVALFHRK 62

  Fly   118 DSRSRLPLGGGSLITRDVVLTSS----TKTLEVPEKYLIVRAGEWDF-ESITEERAHEDVAIRKI 177
            |::..... |||::..:.:||:|    |::..:....:.|..|.... ||....:.|   .:|:|
Mosquito    63 DAQYEYAC-GGSILDENTILTASHCVYTQSGVISISRVSVDVGRIHLNESSEYTQTH---LVREI 123

  Fly   178 VRHTNLSVENGANNAALLFLARPLKLDHHIGLICL--PPPNRNFI--HNRCIVSGWGKKTALDNS 238
            :.|...|..:..|:.||:.|:..:.::.::..:||  ...|:..|  .|..|| |:|...  .:.
Mosquito   124 IVHPGFSKNSIVNDIALIKLSSNITMNKYVQPVCLWTMDSNQELIVGRNGTIV-GFGVNE--QDV 185

  Fly   239 YMNILKKIELPLVDRSVCQTKLQGPYGKDFILDNSLICAGGEPGKDTCKGDGGAPLACPLQSDPN 303
            ....||:..:.:||...|....:|.:|..  |.:.:.|..|:.|...|.||.|..:...:   ..
Mosquito   186 VSEQLKQALIGVVDPLSCIADDRGVFGTH--LTSDMFCGKGQKGVSACNGDSGGGMFFEI---GG 245

  Fly   304 RYELLGIVNF-GFG---CGGPLPAAYTDVSQIRSWIDNCIQAEAVHYSPQLGNV 353
            ::.:.|:|:| ..|   |......|||||::...||...|....:.|...:.|:
Mosquito   246 KWFVRGLVSFTPLGTEQCDSLKNTAYTDVAKYLEWIKPYIDQRVLSYDSDVLNI 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4793	NP_723941.2	Tryp_SPc	105..337	CDD:238113	64/247 (26%)
CG4793	NP_723941.2	Tryp_SPc	105..335	CDD:214473	62/245 (25%)
AgaP_AGAP011669	XP_320844.4	Tryp_SPc	41..282	CDD:238113	66/253 (26%)
		Tryp_SPc	43..281	CDD:214473	64/250 (26%)
		Tryp_SPc	330..568	CDD:214473
		Tryp_SPc	330..568	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910